Yin Tianxiang, Zhou Xingnan, Shi Jing
School of Chemistry and Molecular Engineering, East China University of Science and Technology Shanghai 200237 China
The Affiliated Huai'an Hospital of Xuzhou Medical University and the Second People's Hospital of Huai'an Huai'an 223002 China.
RSC Adv. 2021 Jul 6;11(39):23968-23974. doi: 10.1039/d1ra03345j.
Carbon dots (CDs) have drawn considerable attention in recent decades due to their outstanding biocompatibility and environmental friendliness. In this study, we synthesized ionic liquid (1-aminopropyl-3-methyl-imidazolium bromide)-modified carbon dots (IL-CDs) showing good peroxidase-like activity. Furthermore, we investigated their enzymic behavior in the presence of two different amphiphilic molecules, namely -butanol (TBA, a typical hydrotrope) and sodium bis (2-ethylhexyl) sulfosuccinate (AOT, a typical anionic surfactant). In an aqueous solution of TBA, a microscopic heterogeneous structure was formed in a certain concentration range of TBA, which resulted in an anomaly in the reaction process. However, in the AOT aqueous solution, the situation became more complicated. IL-CDs formed vesicles or precipitation at different concentrations of AOT, which led to different enzymic activities of IL-CDs due to the variance in the structure and the surface electronic density.
近几十年来，碳点（CDs）因其出色的生物相容性和环境友好性而备受关注。在本研究中，我们合成了具有良好类过氧化物酶活性的离子液体（1-氨丙基-3-甲基咪唑溴盐）修饰的碳点（IL-CDs）。此外，我们研究了它们在两种不同两亲分子存在下的酶促行为，这两种两亲分子分别是叔丁醇（TBA，一种典型的助溶剂）和双（2-乙基己基）磺基琥珀酸钠（AOT，一种典型的阴离子表面活性剂）。在TBA水溶液中，在TBA的一定浓度范围内形成了微观非均相结构，这导致反应过程出现异常。然而，在AOT水溶液中，情况变得更加复杂。IL-CDs在不同浓度的AOT下形成囊泡或沉淀，由于结构和表面电子密度的差异，这导致了IL-CDs不同的酶活性。
