Sajnani Ravin, Karapetian Elena, Golla Abhinav, Tsui Irena, Sarraf David
Stein Eye Institute, University of California - Los Angeles, 100 Stein Plaza Driveway, Los Angeles, CA, 90095, USA.
Greater Los Angeles VA Healthcare Center, West Los Angeles Veterans Affairs Hospital, Department of Ophthalmology, 11301 Wilshire Boulevard, Los Angeles, CA, 90073, USA.
Am J Ophthalmol Case Rep. 2022 Apr 3;26:101498. doi: 10.1016/j.ajoc.2022.101498. eCollection 2022 Jun.
To describe a case of peripheral retinal neovascularization and its possible etiological connection to comorbid obstructive sleep apnea.
In this case report we describe a diabetic patient with obstructive sleep apnea who presented with bilateral peripheral retinal neovascularization but in the absence of any other evidence of diabetic retinopathy. Aside from confirmed nocturnal hypoxia and reasonably controlled diabetes mellitus, etiological investigation was otherwise unrevealing.
In the absence of typical findings for diabetic retinopathy, nocturnal hypoxia due to obstructive sleep apnea may be a contributing factor in the development of peripheral retinal neovascularization. There may be a role for more vigilant OSA screening in patients with peripheral retinal neovascularization as treatment with positive airway pressure devices may reduce the retinal hypoxic burden.
描述一例周边视网膜新生血管病例及其与合并存在的阻塞性睡眠呼吸暂停可能的病因学联系。
在本病例报告中，我们描述了一名患有阻塞性睡眠呼吸暂停的糖尿病患者，该患者出现双侧周边视网膜新生血管，但无糖尿病视网膜病变的任何其他证据。除了确诊的夜间低氧血症和控制良好的糖尿病外，病因学调查未发现其他异常。
在没有糖尿病视网膜病变典型表现的情况下，阻塞性睡眠呼吸暂停导致的夜间低氧血症可能是周边视网膜新生血管形成的一个促成因素。对于周边视网膜新生血管患者，更积极的阻塞性睡眠呼吸暂停筛查可能具有重要意义，因为使用气道正压装置进行治疗可能会减轻视网膜缺氧负担。
