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一种新型超顺磁性的、功能化胍基的γ-FeO基磺酸可回收高效多相催化剂，用于在绿色介质中微波辅助快速合成喹唑啉-4(3)-酮衍生物。

A novel superparamagnetic powerful guanidine-functionalized γ-FeO based sulfonic acid recyclable and efficient heterogeneous catalyst for microwave-assisted rapid synthesis of quinazolin-4(3)-one derivatives in Green media.

作者信息

Norouzi Fateme Haji, Foroughifar Naser, Khajeh-Amiri Alireza, Pasdar Hoda

机构信息

Department of Chemistry, Tehran North Branch, Islamic Azad University Tehran Iran

Toxicology Research Center, Aja University of Medical Sciences Tehran Iran.

出版信息

RSC Adv. 2021 Sep 7;11(48):29948-29959. doi: 10.1039/d1ra05560g. eCollection 2021 Sep 6.

DOI:10.1039/d1ra05560g
PMID:35480261
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9040894/
Abstract

The novel organic-inorganic nanohybrid superparamagnetic (γ-FeO@CPTMS-guanidine@SOH) nanocatalyst modified with sulfonic acid represents an efficient and green catalyst for the one-pot synthesis of quinazolin-4(3)-one derivatives three-component condensation reaction between anthranilic acid, acetic anhydride and different amines under microwave irradiation and solvent-free conditions (4a-q). XRD, FT-IR, FE-SEM, TGA, VSM and EDX were used to characterize this new magnetic organocatalyst. Outstanding performance, short response time (15-30 min), simple operation, easy work-up procedure, and avoidance of toxic catalysts can be regarded as its significant advantages. Moreover, it can be easily separated from the reaction solution through magnetic decantation using an external magnet, and recycled at least six times without notable reduction in its activity.

摘要

用磺酸修饰的新型有机-无机纳米杂化超顺磁性（γ-FeO@CPTMS-胍@SOH）纳米催化剂是一种高效、绿色的催化剂，可在微波辐射和无溶剂条件下，通过邻氨基苯甲酸、乙酸酐与不同胺之间的三组分缩合反应一锅法合成喹唑啉-4(3)-酮衍生物（4a-q）。采用X射线衍射（XRD）、傅里叶变换红外光谱（FT-IR）、场发射扫描电子显微镜（FE-SEM）、热重分析（TGA）、振动样品磁强计（VSM）和能谱分析（EDX）对这种新型磁性有机催化剂进行了表征。其显著优点包括性能优异、响应时间短（15 - 30分钟）、操作简单、后处理程序简便以及避免使用有毒催化剂。此外，使用外部磁铁通过磁性倾析法可轻松将其从反应溶液中分离出来，并且至少可循环使用六次，其活性无明显降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9040894/8151d44c2b51/d1ra05560g-f7.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9040894/ca8de316207c/d1ra05560g-f6.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9040894/1cf2d3131d2c/d1ra05560g-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d70/9040894/562e87dedd7d/d1ra05560g-f1.jpg
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2
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3
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8
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Tetrahedron Lett. 2011 Dec 7;52(49):6643-6645. doi: 10.1016/j.tetlet.2011.10.012.
9
Magnetically separable nanocatalysts: bridges between homogeneous and heterogeneous catalysis.磁性可分离纳米催化剂：均相催化与多相催化之间的桥梁。
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10
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