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J Biomed Nanotechnol. 2020 Nov 1;16(11):1600-1611. doi: 10.1166/jbn.2020.2989.
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6-Shogaol from ginger shows anti-tumor effect in cervical carcinoma via PI3K/Akt/mTOR pathway.姜烯酚通过 PI3K/Akt/mTOR 通路显示出对宫颈癌的抗肿瘤作用。
Eur J Nutr. 2021 Aug;60(5):2781-2793. doi: 10.1007/s00394-020-02440-9. Epub 2021 Jan 8.
3
HIV Protease Inhibitors Block HPV16-Induced Murine Cervical Carcinoma and Promote Vessel Normalization in Association with MMP-9 Inhibition and TIMP-3 Induction.HIV 蛋白酶抑制剂抑制 HPV16 诱导的小鼠宫颈肿瘤,并通过抑制 MMP-9 和诱导 TIMP-3 促进血管正常化。
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HeLa Cell-Derived Paclitaxel-Loaded Microparticles Efficiently Inhibit the Growth of Cervical Carcinoma.HeLa 细胞来源的紫杉醇载入微球能有效抑制宫颈癌生长。
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Photodynamic Effects of Vitamin K3 on Cervical Carcinoma Cells Activating Mitochondrial Apoptosis Pathways.维生素 K3 对宫颈癌细胞的光动力作用激活线粒体凋亡途径。
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Uterine Cervical Carcinoma: Evaluation Using Non-Gaussian Diffusion Kurtosis Imaging and Its Correlation With Histopathological Findings.子宫颈癌:使用非高斯扩散峰度成像的评估及其与组织病理学结果的相关性
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Sentinel lymph node biopsy alone in the management of early cervical carcinoma.前哨淋巴结活检单独用于早期宫颈癌的管理。
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A prognostic nomogram integrating novel biomarkers identified by machine learning for cervical squamous cell carcinoma.一种整合通过机器学习识别的新型生物标志物的子宫颈鳞状细胞癌预后列线图。
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凯格尔盆底肌锻炼联合间歇性清洁导尿对宫颈癌根治术后尿潴留的影响

Effect of Kegel Pelvic Floor Muscle Exercise Combined with Clean Intermittent Self-catheterization on urinary retention after radical hysterectomy for cervical cancer.

作者信息

Zong Jingjing, You Minghui, Li Chen

机构信息

Jingjing Zong, Department of Reproductive Medicine, Baoding First Central Hospital, Baoding, Hebei, 071000, China.

Minghui You, Department of Anoenterology, Shandong Second Provncial Generat Hospital (Shandong Provincial ENT Hospital), Jinan, Shandong, 250000, China.

出版信息

Pak J Med Sci. 2022 Mar-Apr;38(3Part-I):462-468. doi: 10.12669/pjms.38.3.4495.

DOI:10.12669/pjms.38.3.4495
PMID:35480547
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9002440/
Abstract

OBJECTIVES

To investigate the effect of Kegel pelvic floor muscle training combined with clean intermittent self-catheterization on patients with cervical cancer, and to analyze the risk factors affecting urinary retention.

METHODS

A total of 166 patients with cervical cancer admitted to our hospital from October 2016 to December 2019, all of whom received radical resection of cervical cancer, were divided into two groups according to the random number table method: the observation group and the control group, with 83 cases in each group. The control group underwent clean intermittent self-catheterization, while the observation group underwent Kegel pelvic floor muscle exercise combined with clean intermittent self-catheterization. The catheter replacement rate, bladder residual urine volume, self-perceived burden scale (SPB), Kolcaba general comfort questionnaire (GCQ), incidence of urinary tract infection, and urinary retention after catheter removal were compared between the two groups. Logistics regression analysis was utilized to analyze the risk factors affecting urinary retention.

RESULTS

The incidence of catheter replacement, urinary retention, dysuria and bladder residual urine volume in the observation group were significantly lower than those in the control group (P<0.05). Postoperative SPB score of the two groups decreased significantly, while the GCQ score increased significantly. Postoperative SPB score of the observation group was significantly lower than that of the control group, while the GCQ score was significantly higher than that of the control group (P<0.05). Statistically significant differences can be observed in the comparison of catheter indwelling time, urinary tract infection, surgical incision infection and surgical margin between the two groups (P<0.05). Logistic regression analysis showed that catheter indwelling time, urinary tract infection, surgical incision infection and surgical margin were independent risk factors affecting urinary retention (P<0.05).

CONCLUSIONS

Catheter indwelling time, urinary tract infection, surgical incision infection and surgical margin are the risk factors for postoperative urinary retention in patients with cervical cancer. With Kegel pelvic floor muscle exercise combined with clean intermittent self-catheterization, a variety of benefits can be realized, such as improved bladder function, reduced incidence of urinary tract infections and urinary retention, as well as increased patient comfort.

摘要

目的

探讨凯格尔盆底肌训练联合清洁间歇性自我导尿对宫颈癌患者的影响,并分析影响尿潴留的危险因素。

方法

选取2016年10月至2019年12月在我院收治的166例宫颈癌患者,均行宫颈癌根治术,根据随机数字表法分为观察组和对照组,每组83例。对照组采用清洁间歇性自我导尿,观察组采用凯格尔盆底肌训练联合清洁间歇性自我导尿。比较两组的导尿管更换率、膀胱残余尿量、自我感知负担量表(SPB)、Kolcaba一般舒适度问卷(GCQ)、尿路感染发生率及拔管后尿潴留情况。采用Logistic回归分析影响尿潴留的危险因素。

结果

观察组的导尿管更换率、尿潴留、排尿困难及膀胱残余尿量发生率均显著低于对照组(P<0.05)。两组术后SPB评分均显著降低,而GCQ评分均显著升高。观察组术后SPB评分显著低于对照组,而GCQ评分显著高于对照组(P<0.05)。两组在导尿管留置时间、尿路感染、手术切口感染及手术切缘比较上有统计学意义(P<0.05)。Logistic回归分析显示,导尿管留置时间、尿路感染、手术切口感染及手术切缘是影响尿潴留的独立危险因素(P<0.05)。

结论

导尿管留置时间、尿路感染、手术切口感染及手术切缘是宫颈癌患者术后尿潴留的危险因素。凯格尔盆底肌训练联合清洁间歇性自我导尿可实现多种益处,如改善膀胱功能、降低尿路感染和尿潴留发生率以及提高患者舒适度。