Ankara University Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey
Turk J Ophthalmol. 2022 Apr 28;52(2):147-152. doi: 10.4274/tjo.galenos.2022.93213.
The aim of this case report is to describe a case of atypical central serous chorioretinopathy (CSCR) definitively diagnosed after 8 years. A 44-year-old woman presented with reduced visual acuity in her left eye. Her visual acuity was light perception with projection in the right eye and 0.15 in the left. She described a similar decline in vision in her right eye 8 years ago. At that time, she had exudative retinal detachment and was treated with systemic immunosuppressive therapy for a presumed diagnosis of Vogt-Koyanagi-Harada disease. Despite resolution of the exudative retinal detachment, macular scarring developed. Eight years later, she developed inferior exudative retinal detachment in the left eye. A diagnosis of atypical CSCR was made with the help of multimodal imaging and her left eye was successfully treated with eplerenone and half-fluence photodynamic therapy (hf-PDT). In conclusion, early diagnosis and treatment of atypical CSCR may prevent subretinal fibrosis formation and permanent vision loss. Hf-PDT and eplerenone are successful treatment options for atypical CSCR.
本病例报告旨在描述一例 8 年后确诊的非典型性中心性浆液性脉络膜视网膜病变（CSCR）。一名 44 岁女性因左眼视力下降就诊。右眼视力为光感伴投影，左眼视力为 0.15。她描述了 8 年前右眼视力类似下降的情况。当时，她患有渗出性视网膜脱离，并接受了全身免疫抑制治疗，拟诊为 Vogt-Koyanagi-Harada 病。尽管渗出性视网膜脱离得到解决，但黄斑区出现了瘢痕。8 年后，左眼出现了下方渗出性视网膜脱离。在多模态成像的帮助下，诊断为非典型 CSCR，左眼成功接受了依普利酮和半剂量光动力疗法（hf-PDT）治疗。总之，早期诊断和治疗非典型 CSCR 可预防视网膜下纤维化形成和永久性视力丧失。hf-PDT 和依普利酮是治疗非典型 CSCR 的有效选择。
