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创伤后应激障碍并不是 COVID-19 大流行的标志性障碍;适应障碍才是。

PTSD is not the emblematic disorder of the COVID-19 pandemic; adjustment disorder is.

机构信息

Research Center of the Douglas Mental Health University Institute (CIUSSS-ODIM), 6875 boulevard LaSalle, Montreal, QC, H4H 1R3, Canada.

Department of Psychiatry, McGill University, Montreal, QC, Canada.

出版信息

BMC Psychiatry. 2022 Apr 28;22(1):300. doi: 10.1186/s12888-022-03903-5.

Abstract

BACKGROUND

Posttraumatic stress disorder (PTSD) has been hailed by some as the emblematic mental disorder of the COVID-19 pandemic, assuming that PTSD's life-threat criterion was met de facto. More plausible outcomes like adjustment disorder (AD) have been overlooked.

METHODS

An online cross-sectional survey was launched in the initial stage of the pandemic using a convenience sample of 5 913 adults to compare the prevalence of COVID-related probable PTSD versus probable AD. The abridged Impact of Event Scale - Revised (IES-6) assessed the severity of trauma- and stressor-related symptoms over the previous week. Demographic and pandemic-related data (e.g., receiving a formal diagnosis of COVID-19, job loss, loss of loved one, confinement, material hardship) were collected. A Classification and Regression Tree analysis was conducted to uncover the pandemic experiences leading to clinical 'caseness'. Caseness was defined by a score > 9 on the IES-6 symptom measure and further characterized as PTSD or AD depending on whether the Peritraumatic Distress Inventory's life-threat item was endorsed or not.

RESULTS

The participants were predominantly Caucasian (72.8%), women (79.2%), with a university degree (85%), and a mean age of 42.22 (SD = 15.24) years; 3 647 participants (61.7%; 95%CI [60.4, 63.0]) met the threshold for caseness. However, when perceived life-threat was accounted for, only 6.7% (95%CI [6.1, 7.4]) were classified as PTSD cases, and 55% (95%CI [53.7, 56.2]) as AD cases. Among the AD cases, three distinct profiles emerged marked by the following: (i) a worst personal pandemic experience eliciting intense fear, helplessness or horror (in the absence, however, of any life-threat), (ii) a pandemic experience eliciting sadness/grief, and (iii) worrying intensely about the safety of significant others.

CONCLUSIONS

Studies considering the life-threat criterion as met de facto during the pandemic are confusing PTSD for AD on most counts. This misconception is obscuring the various AD-related idioms of distress that have emerged during the pandemic and the actual treatment needs.

摘要

背景

创伤后应激障碍(PTSD)被一些人誉为 COVID-19 大流行的标志性精神障碍,假设 PTSD 的生命威胁标准实际上已经得到满足。而更合理的结果,如适应障碍(AD),则被忽视了。

方法

在大流行的初始阶段,使用便利样本对 5913 名成年人进行了一项在线横断面调查,以比较与 COVID 相关的可能 PTSD 与可能 AD 的患病率。缩短版事件影响量表修订版(IES-6)评估了过去一周与创伤和应激源相关的症状严重程度。收集了人口统计学和大流行相关数据(例如,被正式诊断为 COVID-19、失业、失去亲人、隔离、物质困难)。进行了分类和回归树分析,以揭示导致临床“病例”的大流行经历。病例的定义是 IES-6 症状测量得分>9,并根据创伤后应激障碍量表的生命威胁项目是否被认可,进一步分为 PTSD 或 AD。

结果

参与者主要为白种人(72.8%)、女性(79.2%)、具有大学学历(85%),平均年龄为 42.22 岁(SD=15.24);3647 名参与者(61.7%[60.4,63.0])符合病例标准。然而,当考虑到感知到的生命威胁时,只有 6.7%(95%CI[6.1,7.4])被归类为 PTSD 病例,55%(95%CI[53.7,56.2])为 AD 病例。在 AD 病例中,出现了三种不同的特征,分别是:(i)经历了最严重的个人大流行事件,引起了强烈的恐惧、无助或恐惧(然而,没有任何生命威胁),(ii)经历了引起悲伤/悲痛的大流行事件,以及(iii)对重要他人的安全感到极度担忧。

结论

在大流行期间,将生命威胁标准视为实际满足的研究在大多数情况下将 PTSD 误认为是 AD。这种误解掩盖了大流行期间出现的各种 AD 相关痛苦模式,以及实际的治疗需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d23d/9047380/3371ede8714c/12888_2022_3903_Fig1_HTML.jpg

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