MD Anderson Cancer Center, Houston, TX.
Harvard Medical School, Brigham and Women's Hospital.
Am J Clin Oncol. 2022 Jun 1;45(6):243-248. doi: 10.1097/COC.0000000000000912. Epub 2022 Apr 29.
AIM/OBJECTIVES/BACKGROUND: The American College of Radiology (ACR), the American Brachytherapy Society (ABS), and the American Society for Radiation Oncology (ASTRO) have jointly developed the following practice parameter for the performance of low-dose-rate (LDR) brachytherapy. LDR brachytherapy is the application of radioactive sources in or on tumors in a clinical setting with therapeutic intent. The advantages of LDR brachytherapy include improving therapeutic ratios with lower doses to nontarget organs-at-risk and higher doses to a specific target.
This practice parameter was developed according to the process described under the heading. The Process for Developing ACR Practice Parameters and Technical Standards on the ACR website (https://www.acr.org/Clinical-Resources/Practice-Parameters-and-Technical-Standards) by the Committee on Practice Parameters-Radiation Oncology of the Commission on Radiation Oncology, in collaboration with ABS and ASTRO.
This practice parameter was developed to serve as a tool in the appropriate application of this evolving technology in the care of cancer patients or other patients with conditions where radiation therapy is indicated. It addresses clinical implementation of LDR brachytherapy including personnel qualifications, quality assurance standards, indications, and suggested documentation. This includes a contemporary literature search.
This practice parameter is a tool to guide the use of LDR brachytherapy and does not assess relative clinical indication for LDR brachytherapy when compared with other forms of brachytherapy or external beam therapy, but to focus on the best practices required to deliver LDR brachytherapy safely and effectively, when clinically indicated. Comparative costs of versus other modalities therapy may also need to be considered.
目的/目标/背景:美国放射学院(ACR)、美国近距离放射治疗学会(ABS)和美国放射肿瘤学会(ASTRO)联合制定了以下低剂量率(LDR)近距离放射治疗的实践参数。LDR 近距离放射治疗是指在临床环境中,具有治疗意图的放射性源在肿瘤内或肿瘤上的应用。LDR 近距离放射治疗的优势包括通过对非靶器官-危险器官给予较低剂量和对特定靶区给予较高剂量,改善治疗比率。
本实践参数是根据标题下所述的过程制定的。该过程由放射肿瘤学委员会实践参数 - 辐射肿瘤学委员会在 ACR 网站(https://www.acr.org/Clinical-Resources/Practice-Parameters-and-Technical-Standards)上描述,与 ABS 和 ASTRO 合作。
本实践参数旨在作为一种工具,帮助在癌症患者或其他需要放射治疗的患者的护理中适当应用这种不断发展的技术。它涉及 LDR 近距离放射治疗的临床实施,包括人员资格、质量保证标准、适应症和建议的文件。这包括当代文献检索。
本实践参数是指导 LDR 近距离放射治疗使用的工具,并不评估 LDR 近距离放射治疗与其他形式的近距离放射治疗或外照射治疗相比的相对临床适应证,而是侧重于在临床需要时安全有效地提供 LDR 近距离放射治疗所需的最佳实践。与其他治疗方式相比的相对成本也可能需要考虑。