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[骨水泥强化与骨移植替代物——材料与生物力学]

[Cement augmentation and bone graft substitutes-Materials and biomechanics].

作者信息

Gueorguiev Boyko, Lenz Mark

机构信息

AO Forschungsinstitut Davos, Clavadelerstraße 8, 7270, Davos, Schweiz.

Klinik für Unfall‑, Hand- und Wiederherstellungschirurgie, Universitätsklinikum Jena, Friedrich-Schiller-Universität Jena, 07747, Jena, Deutschland.

出版信息

Unfallchirurgie (Heidelb). 2022 Jun;125(6):430-435. doi: 10.1007/s00113-022-01182-z. Epub 2022 Apr 29.

Abstract

BACKGROUND

Materials with different characteristics are used for cement augmentation and as bone graft substitutes.

OBJECTIVE

Cement augmentation and bone graft substitutes are the subject of current research. The evaluation of new knowledge allows its specific application.

MATERIAL AND METHODS

Selective literature search and outline of experimental research results on cement augmentation and bone graft substitutes.

RESULTS

Augmentation and bone graft substitutes are essential components of current trauma surgical procedures. Despite intensive research all materials have specific disadvantages. Cement augmentation of implants enhances not only the anchorage but also influences the failure mode.

CONCLUSION

Cement augmentation has large potential especially in osteoporotic bone. In load-bearing regions acrylic-based cements remain the standard of choice. Ceramic cements are preferred in non-load-bearing areas. Their combination with resorbable metals offers still largely unexplored potential. Virtual biomechanics can help improve the targeted application of cement augmentation.

摘要

背景

具有不同特性的材料被用于骨水泥强化及作为骨移植替代物。

目的

骨水泥强化及骨移植替代物是当前研究的主题。对新知识的评估有助于其具体应用。

材料与方法

对骨水泥强化及骨移植替代物的实验研究结果进行选择性文献检索并概述。

结果

强化及骨移植替代物是当前创伤外科手术的重要组成部分。尽管进行了深入研究,但所有材料都有特定的缺点。植入物的骨水泥强化不仅增强了锚固力,还影响失效模式。

结论

骨水泥强化具有很大潜力,尤其是在骨质疏松性骨中。在承重区域,丙烯酸基骨水泥仍是首选标准。陶瓷骨水泥在非承重区域更受青睐。它们与可吸收金属的组合仍有很大未开发的潜力。虚拟生物力学有助于改善骨水泥强化的靶向应用。

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