土耳其狂犬病毒田间分离株全 G 和 N 基因序列比较。
The comparison of full G and N gene sequences from turkish rabies virus field strains.
机构信息
Etlik Veterinary Control Central Research Institute, Rabies Laboratory, 06220 Ankara, Turkey.
Ankara University Veterinary Faculty Department of Virology, 06110 Dışkapı Ankara, Turkey.
出版信息
Virus Res. 2022 Jul 2;315:198790. doi: 10.1016/j.virusres.2022.198790. Epub 2022 Apr 27.
The rabies infection is a zoonotic viral disease in humans and is spread by both wild and domestic carnivores. This study aimed to molecularly characterize the field strains of the rabies virus circulating in Turkey between 2013 and 2020. Brain samples obtained from 16 infected animals (eight cattle, one donkey, three foxes, three dogs, and one marten) were tested. Full nucleoprotein (N) and glycoprotein (G) gene sequences were used to determine the genetic and antigenic characteristics of the rabies virus field strains. The phylogenetic analyses revealed that the 16 field strains identified in Turkey belonged to the Cosmopolitan lineage.
狂犬病是一种人兽共患的病毒性疾病，由野生和家养食肉动物传播。本研究旨在对 2013 年至 2020 年期间在土耳其流行的狂犬病病毒的田间分离株进行分子特征分析。对来自 16 只感染动物（8 头牛、1 只驴、3 只狐狸、3 只狗和 1 只貂）的脑组织样本进行了检测。利用全长核蛋白（N）和糖蛋白（G）基因序列来确定狂犬病病毒田间分离株的遗传和抗原特征。系统进化分析表明，在土耳其鉴定的 16 株田间分离株属于世界性谱系。
Zotero 插件