疱疹性眼病的阿昔洛韦合理治疗
Rational acyclovir therapy in herpetic eye disease.
作者信息
Falcon M G
出版信息
Br J Ophthalmol. 1987 Feb;71(2):102-6. doi: 10.1136/bjo.71.2.102.
Abstract
Acyclovir has been widely used against the various manifestations of eye disease due to herpes simplex since it first became generally available in the UK nearly five years ago. This paper discusses the rational indications for its use, through considerations of its pharmacology and pharmacokinetics, and through results of the many clinical trials that have been carried out to investigate its effects since its clinical efficacy was first demonstrated in 1979.
摘要
自近五年前阿昔洛韦在英国普遍上市以来，它已被广泛用于治疗单纯疱疹所致的各种眼部疾病表现。本文通过对其药理学和药代动力学的考量，以及自1979年首次证明其临床疗效以来为研究其效果而开展的众多临床试验结果，探讨其合理的用药指征。
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Rational acyclovir therapy in herpetic eye disease.疱疹性眼病的阿昔洛韦合理治疗
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本文引用的文献
1
Herpetic iridocyclitis.疱疹性虹膜睫状体炎
Int Ophthalmol. 1982 Feb;4(3):143-50. doi: 10.1007/BF00161904.
2
A comparison of acyclovir and idoxuridine as treatment for ulcerative herpetic keratitis.阿昔洛韦与碘苷治疗溃疡性疱疹性角膜炎的比较。
Br J Ophthalmol. 1980 Oct;64(10):763-5. doi: 10.1136/bjo.64.10.763.
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Prognosis and management of corneal transplantation for herpetic keratitis.
Arch Ophthalmol. 1980 Oct;98(10):1755-9. doi: 10.1001/archopht.1980.01020040607002.
4
The role of herpesvirus type 1 thymidine kinase in experimental ocular infections.
Am J Ophthalmol. 1983 Feb;95(2):175-81. doi: 10.1016/0002-9394(83)90011-9.
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Herpesvirus inoculation of cornea.
Am J Ophthalmol. 1984 Apr;97(4):482-7. doi: 10.1016/s0002-9394(14)76132-x.
6
Topical treatment of experimental herpes simplex keratouveitis with 2'-O-glycylacyclovir. A water-soluble ester of acyclovir.用2'-O-甘氨酰阿昔洛韦对实验性单纯疱疹性角膜葡萄膜炎进行局部治疗。阿昔洛韦的一种水溶性酯。
Arch Ophthalmol. 1984 Jan;102(1):140-2. doi: 10.1001/archopht.1984.01040030118049.
7
Pharmacokinetics of oral acyclovir (Zovirax) in the eye.口服阿昔洛韦（无环鸟苷）在眼部的药代动力学。
Br J Ophthalmol. 1984 Mar;68(3):192-5. doi: 10.1136/bjo.68.3.192.
8
Herpes simplex chorioretinitis in a healthy adult.
Am J Ophthalmol. 1983 Dec;96(6):788-96. doi: 10.1016/s0002-9394(14)71925-7.
9
Acute retinal necrosis.
Am J Ophthalmol. 1983 Nov;96(5):683-5. doi: 10.1016/s0002-9394(14)73430-0.
10
Acyclovir in the treatment of herpetic stromal disease.阿昔洛韦治疗疱疹性基质疾病。
Am J Ophthalmol. 1984 Nov;98(5):537-47. doi: 10.1016/0002-9394(84)90237-x.
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