Vorontsov A V, Babaeva D M, Vladimirova V P, Dubovitskaya T A, Gavrilova A O, Belaya Zh E, Mokryshevа N G
Endocrinology Research Centre.
Probl Endokrinol (Mosk). 2022 Jan 25;68(2):16-33. doi: 10.14341/probl12777.
This article presents a literature review of the various forms of hypophysitis, its varieties, as well as the problem of radiation diagnosis and treatment of this pathology. Hypophysitis is a poorly understood and multifactorial disease which the difficulty of diagnosing is not only to a variety of nonspecific clinical manifestations and hormonal research data, but also the ambiguous results of MRI studies, the lack of clear MR patterns. The article reflects the main histological types of hypophysitis, the peculiarities of diagnosis in connection with general clinical symptoms, outlines the features of each type of hypophysitis with their own clinical observations. This review is devoted to modern ideas about the clinical course of hypophysitis, presented a set of characteristic diagnostic signs of the disease according to MRI and the treatment algorithms recommended today are also highlighted. The article summarizes data from foreign literature and our own clinical observations in order to develop an optimal protocol for MRI studies in patients with suspected hypophysitis, to develop recommendations for radiologists and endocrinologists for the correct results interpretation. The uniqueness of this review is the lack of data on the clinic, diagnosis and treatment of hypophysitis in the Russian literature today.
本文对垂体炎的各种形式、其类型以及该病理学的放射诊断和治疗问题进行了文献综述。垂体炎是一种了解不足且多因素的疾病，其诊断困难不仅在于各种非特异性临床表现和激素研究数据，还在于MRI研究结果不明确、缺乏清晰的MR模式。文章反映了垂体炎的主要组织学类型、与一般临床症状相关的诊断特点，概述了每种类型垂体炎的特征及临床观察结果。本综述致力于关于垂体炎临床病程的现代观点，呈现了根据MRI得出的该疾病一组特征性诊断体征，还突出了当今推荐的治疗算法。文章总结了来自国外文献和我们自己临床观察的数据，以便制定疑似垂体炎患者MRI研究的最佳方案，为放射科医生和内分泌科医生正确解读结果制定建议。本综述的独特之处在于目前俄罗斯文献中缺乏关于垂体炎临床、诊断和治疗的数据。
