Maxillofacial Surgery Department, Ahmadu Bello University Teaching Hospital, Zaria, Kaduna State, Nigeria.
Pathology Department, Ahmadu Bello University Teaching Hospital, Zaria, Kaduna State, Nigeria.
West Afr J Med. 2022 Apr 29;39(4):350-354.
Ameloblastoma is an aggressive tumor of odontogenic epithelium that grows slowly with propensity for bone expansion. Sometimes it may grow to very large sizes also known as giant ameloblastoma (GA) which may affect function and even pose a threat to life.
To present the pattern of presentation of GAs seen in a tertiary centre in Northern Nigeria.
A retrospective study of patients seen with GA at the Oral and Maxillofacial Clinic of a tertiary health facility of Northern Nigeria between January 2006 to December 2019. All patients with complete documentation in the folder, theatre register and histopathologic records were recruited for the study. Data were analyzed using SPSS version 23.
GAs accounted for 30.2% (48) of all the ameloblastomas operated during the period with a male dominance of 62.5% (30), giving a ratio of 1.7:1(M:F). The age range was between 12 and 65 years with a mean age of 35.04years (±14.5) and the mandible was the most affected jaw compared to the maxilla (12.5%). Lesions with lowest and highest weight were found on the mandible (77g and 1640g respectively). The treatment most given was mandibulectomy (unspecified) with 20.0% followed by Rt and Lt mandibulectomies with 14.0% each.
GA was found to account for 30.2% of all lesions seen within the period under review, while the mandible was the most affected jaw bone.
成釉细胞瘤是一种具有侵袭性的牙源性上皮肿瘤，生长缓慢，有骨膨胀倾向。有时它可能会长得非常大，也被称为巨大型成釉细胞瘤（GA），这可能会影响功能，甚至对生命构成威胁。
介绍尼日利亚北部一家三级中心所见 GA 的表现模式。
对 2006 年 1 月至 2019 年 12 月期间在尼日利亚北部一家三级医疗机构口腔颌面诊所就诊的 GA 患者进行回顾性研究。所有文件夹、手术室登记册和组织病理学记录完整的患者均被招募入组。使用 SPSS 版本 23 分析数据。
GA 占该期间所有行手术治疗的成釉细胞瘤的 30.2%（48 例），男性占 62.5%（30 例），男女比例为 1.7:1（M:F）。年龄范围为 12 至 65 岁，平均年龄为 35.04 岁（±14.5），下颌骨比上颌骨更容易受影响（12.5%）。最低和最高重量的病变分别位于下颌骨（77g 和 1640g）。最常给予的治疗是下颌骨部分切除术（未指定），占 20.0%，其次是右侧和左侧下颌骨部分切除术，各占 14.0%。
GA 占本研究期间所见所有病变的 30.2%，下颌骨是最受影响的颌骨。
