Department of Internal Medicine, Division of Geriatrics, Faculty of Medicine, Marmara University, Istanbul, Turkey.
Department of Pulmonary Medicine, Faculty of Medicine, Marmara University, Istanbul, Turkey.
Nutr Clin Pract. 2022 Jun;37(3):605-614. doi: 10.1002/ncp.10860. Epub 2022 Apr 30.
Although numerous studies have been performed to determine predictors of coronavirus disease 2019 (COVID-19) mortality, studies that address the geriatric age group are limited. The aim of this study was to investigate the utility of the Nutritional Risk Screening 2002 (NRS-2002) and the Geriatric 8 (G8) screening tools in predicting clinical outcomes in older adults hospitalized with COVID-19.
Patients aged ≥60 years who were hospitalized with COVID-19 in the second wave of the pandemic were included in the study. COVID-19 infection was demonstrated by a positive real-time reverse transcriptase-polymerase chain reaction on nasopharyngeal swab or positive radiological findings. Disease severity was determined as defined by the National Institutes of Health. Patient demographics, laboratory values on admission, comorbidities, and medications were recorded. The NRS-2002 and the G8 screening tools were performed for all patients by the same geriatrician. Primary outcome was in-hospital mortality.
A total of 121 patients were included. Mean age was 75 ± 9 years, and 51% were female. Mean body mass index was 27 ± 4.5 kg/m . Sixty-nine percent of the patients had nutrition risk according to the NRS-2002. Eighty-nine percent of the patients had a G8 score ≤14. In-hospital mortality occurred in 26 (22%) patients. Older age and having nutrition risk as determined by the NRS-2002 were independently associated with a higher risk of in-hospital mortality in older patients with COVID-19.
The NRS-2002 tool provides rapid assessment for risk stratification in hospitalized older patients with COVID-19.
尽管已经进行了许多研究来确定 2019 年冠状病毒病(COVID-19)死亡率的预测因素,但针对老年人群的研究有限。本研究旨在探讨营养风险筛查 2002 版(NRS-2002)和老年 8 项(G8)筛查工具在预测 COVID-19 住院老年患者临床结局中的作用。
本研究纳入了在第二波大流行期间因 COVID-19 住院的年龄≥60 岁的患者。通过鼻咽拭子的实时逆转录-聚合酶链反应阳性或影像学阳性结果证实 COVID-19 感染。疾病严重程度按照美国国立卫生研究院的标准定义。记录患者的人口统计学资料、入院时的实验室值、合并症和药物治疗情况。由同一位老年病医生对所有患者进行 NRS-2002 和 G8 筛查。主要结局为住院期间死亡率。
共纳入 121 例患者,平均年龄为 75±9 岁,51%为女性,平均体重指数为 27±4.5kg/m2。69%的患者根据 NRS-2002 存在营养风险。89%的患者 G8 评分≤14。26 例(22%)患者住院期间死亡。年龄较大和 NRS-2002 确定的存在营养风险与 COVID-19 住院老年患者的住院死亡率较高独立相关。
NRS-2002 工具可快速评估 COVID-19 住院老年患者的风险分层。