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入院时的营养风险与 COVID-19 老年患者的住院时间延长有关。

Nutritional risk at hospital admission is associated with prolonged length of hospital stay in old patients with COVID-19.

机构信息

Division of Geriatrics, University Hospitals of Geneva and University of Geneva, Chemin du Pont-Bochet 3, Geneva, Switzerland.

Division of Internal Medicine for the Aged, University Hospitals of Geneva and University of Geneva, Chemin du Pont-Bochet 3, Geneva, Switzerland.

出版信息

Clin Nutr. 2022 Dec;41(12):3085-3088. doi: 10.1016/j.clnu.2021.03.017. Epub 2021 Mar 23.

Abstract

BACKGROUND & AIMS: To investigate the association of nutritional risk at admission with the length of hospital stay (LOS) and mortality in older patients with COVID-19.

METHODS

Retrospective monocentric study in an acute geriatric hospital. Data were collected after an extensive review of medical records and the nutritional risk was assessed according to the Nutritional Risk Screening (NRS). Univariate and multivariate (adjusted for age, sex and comorbidity burden) Cox proportional-hazard and linear regression models were used to investigate the association with the above-mentioned outcomes.

RESULTS

Of a total of 245 patients (86.1 ± 6.4 yrs), 50.6% had a severe nutritional risk with an NRS≥5/7 at admission. Lower BMI, cognitive impairment and swallowing disorders were more prevalent in the patients with a higher NRS. A NRS≥5 was not associated with mortality but prolonged by more than 3 days the LOS among the 173 survivors (β 3.69; 0.71-6.67 95% CI; p = 0.016), with a discharge rate delayed by 1.8 times (HR 0.55; 0.37-0.83 95% CI; p = 0.101).

CONCLUSION

Among the survivors of COVID-19 in an acute geriatric hospital, a NRS ≥5 at admission was associated with a longer LOS, but not with mortality.

摘要

背景与目的

研究入院时的营养风险与 COVID-19 老年患者的住院时间(LOS)和死亡率的关系。

方法

这是一项在急性老年病医院进行的回顾性单中心研究。通过对病历进行广泛审查收集数据,并根据营养风险筛查(NRS)评估营养风险。使用单变量和多变量(调整年龄、性别和合并症负担)Cox 比例风险和线性回归模型来研究与上述结果的关系。

结果

共纳入 245 例患者(86.1±6.4 岁),50.6%的患者入院时存在严重营养风险,NRS≥5/7。较低的 BMI、认知障碍和吞咽障碍在 NRS 较高的患者中更为常见。NRS≥5 与死亡率无关,但在 173 例幸存者中使 LOS 延长了 3 天以上(β 3.69;0.71-6.67 95%CI;p=0.016),出院率延迟了 1.8 倍(HR 0.55;0.37-0.83 95%CI;p=0.101)。

结论

在急性老年病医院 COVID-19 幸存者中,入院时 NRS≥5 与 LOS 延长有关,但与死亡率无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/208a/7985608/7436e9bd4193/gr1_lrg.jpg

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