Division of Cardiology, University of Texas Health San Antonio, USA.
Division of Cardiology, University of Texas Health San Antonio, USA.
Indian Heart J. 2022 May-Jun;74(3):170-177. doi: 10.1016/j.ihj.2022.04.008. Epub 2022 Apr 29.
Coronavirus disease-2019 (COVID-19) has been associated with pre-existing cardiac conditions as well as cardiovascular complications. The incidence rates of cardiac complications, age, and gender differences in this population are unknown.
We wanted to study the incidence of cardiac complications and mortality in patients with COVID-19.
Data from the TriNetX COVID-19 global research network platform was used to identify COVID-19 patients. We compared patients with and without cardiac complications in patients with COVID-19 and obtained survival data.
The final cohort was composed of 81,844 patients with COVID-19. Cardiac complications occurred in 9.3% of patients as follows: acute coronary syndromes in 1.3%, heart failure in 4.4%, atrial fibrillation in 4.5%, sinus bradycardia 1.9%, ventricular tachycardia in 0.5% and complete heart block in 0.01%. Mortality was significantly higher in patients with the cardiac complications mentioned (20%) than in those without them (2.9%) (odds ratio 7.2, 95% CI, 6.7-7.7; p < 0.0001). Older males seem to have higher incidence of cardiac complications and mortality.
Patients with COVID-19 who have cardiac complications have a higher risk of mortality when compared to those without cardiac complications.
新冠肺炎（COVID-19）与先前存在的心脏疾病以及心血管并发症有关。目前尚不清楚该人群中心血管并发症的发生率、年龄和性别差异。
我们旨在研究 COVID-19 患者中心脏并发症和死亡率的发生情况。
我们使用 TriNetX COVID-19 全球研究网络平台的数据来确定 COVID-19 患者，并比较了 COVID-19 患者中有和无心脏并发症患者的情况，并获得了生存数据。
最终的队列由 81844 例 COVID-19 患者组成。9.3%的患者发生了心脏并发症，包括急性冠状动脉综合征（1.3%）、心力衰竭（4.4%）、心房颤动（4.5%）、窦性心动过缓（1.9%）、室性心动过速（0.5%）和完全性心脏传导阻滞（0.01%）。有上述心脏并发症的患者死亡率明显高于无心脏并发症的患者（20%比 2.9%）（比值比 7.2，95%置信区间，6.7-7.7；p<0.0001）。年龄较大的男性似乎有更高的心脏并发症发生率和死亡率。
与无心脏并发症的 COVID-19 患者相比，有心脏并发症的 COVID-19 患者的死亡率更高。
