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钇催化的比鲁姆-奥莱克西辛反应一锅法合成α-氨基膦酸酯

One-pot synthesis of α-aminophosphonates by yttrium-catalyzed Birum-Oleksyszyn reaction.

作者信息

Ceradini Davide, Shubin Kirill

机构信息

Latvian Institute of Organic Synthesis 21 Aizkraukles St. Riga LV-1006 Latvia

出版信息

RSC Adv. 2021 Dec 8;11(62):39147-39152. doi: 10.1039/d1ra07718j. eCollection 2021 Dec 6.

DOI:10.1039/d1ra07718j
PMID:35492473
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9044477/
Abstract

For the first time, yttrium triflate was used as an efficient green catalyst for the synthesis of α-aminophosphonates through a one-pot three-component Birum-Oleksyszyn reaction. Under the action of this Lewis acid, enhancement of the yield and reaction chemoselectivity was provided by the achievement of an appropriate balance in the complex network of reactions.

摘要

首次将三氟甲磺酸钇用作一种高效的绿色催化剂，通过一锅法三组分Birum-Oleksyszyn反应合成α-氨基膦酸酯。在这种路易斯酸的作用下，通过在复杂的反应网络中实现适当的平衡，提高了产率和反应化学选择性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/9044477/023cfd00647d/d1ra07718j-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/9044477/b9ae5211bb1a/d1ra07718j-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/9044477/743ba13e5a09/d1ra07718j-s2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/9044477/1a53db8067c5/d1ra07718j-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/9044477/023cfd00647d/d1ra07718j-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/9044477/b9ae5211bb1a/d1ra07718j-s1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/9044477/743ba13e5a09/d1ra07718j-s2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/9044477/1a53db8067c5/d1ra07718j-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a64b/9044477/023cfd00647d/d1ra07718j-f2.jpg

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