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酿酒酵母线粒体基因组的一级结构——综述

The primary structure of the mitochondrial genome of Saccharomyces cerevisiae--a review.

作者信息

de Zamaroczy M, Bernardi G

出版信息

Gene. 1986;47(2-3):155-77. doi: 10.1016/0378-1119(86)90060-0.

DOI:10.1016/0378-1119(86)90060-0
PMID:3549452
Abstract

We have collated and compiled all the available primary structure data on the mitochondrial genome of Saccharomyces cerevisiae. Data concern 78,500 bp, namely 92% of the 'long' genomes; they are derived from several laboratory strains. Interstrain differences belong to three classes: a small number of large deletions/additions, mainly concerning introns; a large number of small (10-150 bp) deletions/additions located in the intergenic sequences; 1-3 bp deletions/additions and point mutations; the interstrain sequence divergence due to the latter, is of the order of 2% for the strains compared; this low value is, however, an overestimate because of sequence mistakes.

摘要

我们已经整理汇编了所有关于酿酒酵母线粒体基因组的可用一级结构数据。数据涉及78,500碱基对,即“长”基因组的92%;它们源自多个实验室菌株。菌株间差异分为三类:少量的大缺失/插入,主要涉及内含子;大量位于基因间序列的小(10 - 150碱基对)缺失/插入;1 - 3碱基对的缺失/插入和点突变;由于后者导致的菌株间序列差异,在所比较的菌株中约为2%;然而,由于序列错误,这个低值是高估的。

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