Adel Noury
Oral and Maxillofacial Surgery Specialist, Cairo, Egypt.
Plast Reconstr Surg Glob Open. 2022 Apr 25;10(4):e4281. doi: 10.1097/GOX.0000000000004281. eCollection 2022 Apr.
The present study was performed to evaluate the effect of repeated botulinum toxin injections and their long-term effects, using a customized injection point and dosage technique in the treatment of excessive gingival display. Twenty women who had gummy smile due to hypermobility of the upper lip or gingival display, ranging from 4 to 6 mm' were included in the study. All patients were injected with Botox injections at different injection points according to the type of smile. Pre- and postoperative measurements were taken by measuring digitally the gingival display at smiling, using Adobe Photoshop software via standardized digital photographs. Patients were followed up at 14 days, 4 months, 8 months, and 12 months. Postoperative measurements showed marked improvement at 14-day follow-up, with a significant reduction in the amount of gingival display. Relapse, however, occurred at 4 months and later. For excessive gingival display, Botox is an effective treatment that lasts for 2-3 months, with almost complete relapse at 4 months. We concluded from the results of our study that, despite repeated Botox injections at two follow-up intervals (4 and 8 months), the theory that repeated Botox injections may offer a permanent effect is still questionable.
本研究旨在评估重复注射肉毒杆菌毒素的效果及其长期影响，采用定制的注射点和剂量技术治疗牙龈过度外露。本研究纳入了20名因上唇活动过度或牙龈外露导致露龈笑的女性，牙龈外露范围为4至6毫米。根据笑容类型，所有患者在不同注射点注射肉毒杆菌毒素。术前和术后通过使用Adobe Photoshop软件，根据标准化数码照片对微笑时的牙龈外露情况进行数字测量。在术后14天、4个月、8个月和12个月对患者进行随访。术后测量显示，在14天的随访中牙龈外露情况有显著改善，牙龈外露量显著减少。然而，在4个月及之后出现了复发。对于牙龈过度外露，肉毒杆菌毒素是一种有效的治疗方法，可维持2至3个月，在4个月时几乎完全复发。我们从研究结果中得出结论，尽管在两个随访间隔（4个月和8个月）进行了重复肉毒杆菌毒素注射，但重复注射肉毒杆菌毒素可能产生永久效果这一理论仍然存在疑问。
