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耳梅毒:青少年男性可逆性听力损失的罕见病因。

Otosyphilis: A Rare Cause of Reversible Hearing Loss in a Teenage Male.

作者信息

He Shan, Messner Anna H, Mirani Gayatri

机构信息

Anesthesiology, Texas Children's Hospital/Baylor College of Medicine, Houston, USA.

Otolaryngology-Head and Neck Surgery, Texas Children's Hospital/Baylor College of Medicine, Houston, USA.

出版信息

Cureus. 2022 Mar 24;14(3):e23468. doi: 10.7759/cureus.23468. eCollection 2022 Mar.

DOI:10.7759/cureus.23468
PMID:35494944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9038597/
Abstract

A high index of suspicion and a thorough neurotologic examination at the onset of presentation are imperative to generate the diagnosis of otosyphilis. Complete audiologic recovery is rare but possible in approximately 20%-25% of patients after appropriate treatment. We present a case of reversible hearing loss secondary to otosyphilis in a teenage male patient with a new diagnosis of human immunodeficiency virus (HIV). Audiology findings were consistent with mixed hearing loss. Lumbar puncture results were consistent with neurosyphilis. Prompt treatment with a 14-day course of intravenous penicillin led to the complete recovery of hearing. In this case report, the pathophysiology, symptomology, and management of otosyphilis are discussed.

摘要

高度怀疑指数以及在就诊初期进行全面的耳科检查对于梅毒耳炎的诊断至关重要。完全听力恢复很少见,但在适当治疗后约20%-25%的患者中是可能的。我们报告一例患有新诊断的人类免疫缺陷病毒(HIV)的青少年男性患者,因梅毒耳炎继发可逆性听力损失。听力学检查结果与混合性听力损失一致。腰椎穿刺结果与神经梅毒一致。静脉注射青霉素14天疗程的及时治疗使听力完全恢复。在本病例报告中,讨论了梅毒耳炎的病理生理学、症状学和治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a5a/9038597/06bde699044b/cureus-0014-00000023468-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a5a/9038597/df2ff1bf7609/cureus-0014-00000023468-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a5a/9038597/a9adf4ad5313/cureus-0014-00000023468-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a5a/9038597/06bde699044b/cureus-0014-00000023468-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a5a/9038597/df2ff1bf7609/cureus-0014-00000023468-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a5a/9038597/a9adf4ad5313/cureus-0014-00000023468-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a5a/9038597/06bde699044b/cureus-0014-00000023468-i03.jpg

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本文引用的文献

1
A Rare Cause of Acute Bilateral Hearing Loss: Otosyphilis.急性双侧听力损失的罕见病因:耳梅毒。
Cureus. 2020 Oct 29;12(10):e11243. doi: 10.7759/cureus.11243.
2
Ocular and neurosyphilis: epidemiology and approach to management.眼与神经梅毒:流行病学与处理方法。
Curr Opin Infect Dis. 2020 Feb;33(1):66-72. doi: 10.1097/QCO.0000000000000617.
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Pediatric otosyphilis-An unusual cause of conductive hearing loss.小儿耳梅毒——传导性听力损失的罕见病因。
Radiol Case Rep. 2019 Nov 9;15(1):65-70. doi: 10.1016/j.radcr.2019.09.038. eCollection 2020 Jan.
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Penicillin G Sodium as a Treatment of Otosyphilis with Hearing Loss.青霉素G钠治疗伴有听力损失的耳梅毒
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Otosyphilis: Resurgence of an Old Disease.耳梅毒:一种古老疾病的再度流行
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Bilateral temporal bone otosyphilis.双侧颞骨耳梅毒
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BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.01.2009.1464. Epub 2009 Oct 14.