Wackett L P, Wanner B L, Venditti C P, Walsh C T
J Bacteriol. 1987 Apr;169(4):1753-6. doi: 10.1128/jb.169.4.1753-1756.1987.
Escherichia coli K-12 can readily mutate to use methylphosphonic acid as the sole phosphorus source by a direct carbon-to-phosphorus (C-P) bond cleavage activity that releases methane and Pi. The in vivo C-P lyase activity is both physiologically and genetically regulated as a member of the phosphate regulon. Since psiD::lacZ(Mu d1) mutants cannot metabolize methylphosphonic acid, psiD may be the structural gene(s) for C-P lyase.
大肠杆菌K-12可以通过一种直接的碳-磷(C-P)键裂解活性轻易地发生突变,以利用甲基膦酸作为唯一的磷源,这种活性会释放甲烷和磷酸根离子。体内的C-P裂解酶活性作为磷酸盐调节子的一员,在生理和遗传上都受到调控。由于psiD::lacZ(Mud1)突变体不能代谢甲基膦酸,psiD可能是C-P裂解酶的结构基因。