Department of Medicine, University of Washington, Seattle, WA.
HIV/STD Program, Public Health-Seattle & King County, Seattle, WA; and.
J Acquir Immune Defic Syndr. 2022 Aug 15;90(5):530-537. doi: 10.1097/QAI.0000000000003005.
Sexual health clinics (SHCs) serve large numbers of patients who might benefit from preexposure prophylaxis (PrEP). Integrating longitudinal PrEP care into SHCs can overburden clinics. We implemented an SHC PrEP program that task shifted most PrEP operations to nonmedical staff, disease intervention specialists (DIS).
We conducted a retrospective cohort analysis of PrEP patients in an SHC in Seattle, WA, from 2014 to 2020 to assess the number of patients served and factors associated with PrEP discontinuation. Clinicians provide same-day PrEP prescriptions, whereas DIS coordinate the program, act as navigators, and provide most follow-up care.
Between 2014 and 2019, 1387 patients attended an initial PrEP visit, 93% of whom were men who have sex with men. The number of patients initiating PrEP per quarter year increased from 20 to 81. The number of PrEP starts doubled when the clinic shifted from PrEP initiation at scheduled visits to initiation integrated into routine walk-in visits. The percentage of visits performed by DIS increased from 3% in 2014 to 45% in 2019. Median duration on PrEP use was 11 months. PrEP discontinuation was associated with non-Hispanic black race/ethnicity [hazard ratio (HR) 1.34, 95% confidence interval (CI) 1.02 to 1.76], age <20 years (HR 2.17, 95% CI: 1.26 to 3.75), age between 20 and 29 years (HR 1.55, 95% CI: 1.06 to 2.28), and methamphetamine use (HR 1.98, 95% CI: 1.57 to 2.49). The clinic had 750 patients on PrEP in the final quarter of 2019.
A demedicalized SHC PrEP model that task shifts most operations to DIS can provide PrEP at scale to high priority populations.
性健康诊所(SHC)为大量可能受益于暴露前预防(PrEP)的患者提供服务。将纵向 PrEP 护理纳入 SHC 可能会使诊所不堪重负。我们实施了一项 SHC PrEP 计划,将大多数 PrEP 操作任务转移给非医疗人员,即疾病干预专家(DIS)。
我们对华盛顿州西雅图的一家 SHC 中的 PrEP 患者进行了回顾性队列分析,以评估服务的患者数量和与 PrEP 停药相关的因素。临床医生提供当日 PrEP 处方,而 DIS 则协调计划、充当导航员并提供大部分后续护理。
2014 年至 2019 年间,有 1387 名患者首次就诊 PrEP,其中 93%为男男性行为者。每季度开始 PrEP 的患者人数从 20 人增加到 81 人。当诊所从定期就诊的 PrEP 启动转变为纳入常规随诊的启动时,PrEP 的启动数量翻了一番。DIS 进行的就诊比例从 2014 年的 3%增加到 2019 年的 45%。PrEP 使用的中位持续时间为 11 个月。PrEP 停药与非西班牙裔黑人种族/民族(危险比 [HR] 1.34,95%置信区间 [CI] 1.02 至 1.76)、年龄<20 岁(HR 2.17,95%CI:1.26 至 3.75)、20 至 29 岁年龄(HR 1.55,95%CI:1.06 至 2.28)和使用甲基苯丙胺(HR 1.98,95%CI:1.57 至 2.49)有关。该诊所 2019 年最后一个季度有 750 名患者服用 PrEP。
将大多数操作任务转移给 DIS 的去医学化 SHC PrEP 模式可以为高优先级人群提供大规模的 PrEP。