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虹膜睫状体眼内肌纤维瘤瘤:一例病例报告及文献复习。

Intraocular myofibroblastoma tumour of the ciliary body: a case report and literature review.

机构信息

Department of Ophthalmology, Qingdao Municipal Hospital, 5 Middle Donghai Road, Shinan District, Qingdao, Shandong, China.

Department of Ophthalmology, Dalian No,3 People's Hospital, No. 40 Qianshan Road,Ganjingzi District, Dalian, Liaoning, China.

出版信息

BMC Ophthalmol. 2022 May 2;22(1):200. doi: 10.1186/s12886-022-02411-0.

Abstract

BACKGROUND

Inflammatory Myofibroblastoma Tumors (IMTs) are extremely tumour rare in the intraocular.

CASE PRESENTATION

A ciliary body tumor was found under slit lamp biomicroscopy in a 55-year-old male first diagnosed with cataract. Then this patient underwent trans-sclera resection via partial lamellar sclerouvectomy and par plans vitrectomy to remove the mass. Hematoxylin and eosin (HE) staining and immunohistochemistry findings showed that the characteristics of the tumor were consistent with IMT.

CONCLUSIONS

We reported a rare case of intraocular IMT, which is confirmed by H&E staining, and IHC positive staining for Vimentin, Desmin and ALK, while negative staining for SMA, S-100, ki-67, CK, CD68, and calponin.

摘要

背景

眼内炎性肌纤维母细胞瘤(IMTs)极为罕见。

病例介绍

一位 55 岁男性因白内障首次就诊时,在裂隙灯生物显微镜下发现睫状体有肿瘤。随后,该患者接受了经巩膜部分板层巩膜切开术联合部分平面玻璃体切除术,以切除该肿块。苏木精-伊红(HE)染色和免疫组织化学结果显示,肿瘤的特征与 IMT 一致。

结论

我们报道了一例罕见的眼内 IMT 病例,该病例通过 HE 染色得到证实,免疫组织化学结果显示波形蛋白、结蛋白和 ALK 阳性染色,而平滑肌肌动蛋白、S-100、ki-67、CK、CD68 和钙调蛋白阴性染色。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf1c/9063157/cf7a9bba0135/12886_2022_2411_Fig1_HTML.jpg

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