Guffey Johnson Jean, Margo Curtis E
Department of Pathology, James A. Haley Veterans Affairs Hospital, Tampa, Florida, USA.
Department of Pathology and Cell Biology, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA; Department of Ophthalmology, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Surv Ophthalmol. 2017 Jul-Aug;62(4):541-545. doi: 10.1016/j.survophthal.2016.12.013. Epub 2017 Jan 7.
Intraocular inflammatory tumefactions large enough to simulate neoplasms are uncommon. We report a patient with a large intraocular inflammatory mass composed of cells with features of histiocytes and myofibroblasts that was associated with lens-induced uveitis. The spindle cell mass appears to have arisen as an exaggerated response to exposed lens fibers. Although information from immunohistochemistry and cytogenetics has advanced the classification of inflammatory tumefactions, this case highlights the challenges in establishing the nature of these lesions.
