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严重真菌感染性眼内炎继发于 SARS-CoV-2 感染:病例报告。

Fulminant fungal endogenous endophthalmitis following SARS-CoV-2 infection: A case report.

机构信息

Anant Bajaj Retina Institute, L.V. Prasad Eye Institute, Mithu Tulsi Chanrai Campus, Bhubaneswar, Odisha, India.

Ophthalmic Plastic Surgery, Orbit and Ocular Oncology Services, L.V. Prasad Eye Institute, Mithu Tulsi Chanrai Campus, Bhubaneswar, Odisha, India.

出版信息

Indian J Ophthalmol. 2022 May;70(5):1819-1821. doi: 10.4103/ijo.IJO_1951_21.

DOI:10.4103/ijo.IJO_1951_21
PMID:35502083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9333037/
Abstract

Systemic corticosteroids and immunocompromised state following SARS-CoV-2 infection can predispose individuals to endogenous endophthalmitis. A 66-year-old gentleman presented with complaints of diminution of vision and redness one week post discharge after hospitalization for COVID-19 infection. Clinical examination suggested fulminant endogenous endophthalmitis which responded poorly even after aggressive treatment requiring evisceration. Culture and gene sequenced analysis confirmed Aspergillus fumigatus to be the causative organism. A high degree of suspicion is warranted in the presence of recent onset of floaters in COVID-19-infected individuals to facilitate early diagnosis and outcomes.

摘要

系统性皮质类固醇和 SARS-CoV-2 感染后的免疫抑制状态可使个体易患内源性眼内炎。一位 66 岁的绅士在因 COVID-19 感染住院后一周出院时出现视力下降和眼红的症状。临床检查提示暴发性内源性眼内炎,即使经过积极治疗(包括眼球摘除术),病情也未见明显好转。培养和基因测序分析证实致病病原体为烟曲霉。对于 COVID-19 感染患者,近期出现飞蚊症时应高度怀疑该病,以便早期诊断和改善预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/9333037/dea0daa8ac7b/IJO-70-1819-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/9333037/24d4bf78b671/IJO-70-1819-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/9333037/dea0daa8ac7b/IJO-70-1819-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/9333037/24d4bf78b671/IJO-70-1819-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f07/9333037/dea0daa8ac7b/IJO-70-1819-g002.jpg

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2
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