生长抑素对离体犬胃经同源血液体外灌注后五肽胃泌素刺激分泌的影响。
Effect of somatostatin on pentagastrin stimulated secretion by isolated canine stomachs, perfused ex vivo with homologous blood.
作者信息
Kowalewski K, Kolodej A, Kocylowski M
出版信息
Digestion. 1978;17(5):441-4. doi: 10.1159/000198148.
PMID:355028
Abstract
The effect of somatostatin on pentagastrin-induced gastric secretion was assessed on 6 isolated canine stomachs perfused ex vivo with homologous blood. Hormones were given at a constant rate into the gastric arterial circulation. Somatostatin caused inhibition of the HCl concentration and output and reduced the secretion volume in all stomachs studied. The output but not the concentration of pepsin was also reduced.
摘要
在6个用同源血液进行离体灌注的犬离体胃上评估了生长抑素对五肽胃泌素诱导的胃分泌的影响。激素以恒定速率注入胃动脉循环。生长抑素在所有研究的胃中均导致盐酸浓度和分泌量的抑制，并减少了分泌体积。胃蛋白酶的分泌量而非浓度也有所降低。
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