Braun S R
Neurol Clin. 1987 Feb;5(1):9-31.
Failure of the respiratory system is the most common cause of death in amyotrophic lateral sclerosis. This is due to weakened respiratory musculature resulting in respiratory failure, ineffective cough, and failure to protect the lungs from aspiration. Treatment is only supportive at present, but mechanical ventilation with either negative or positive pressure offer some life-extending possibilities. The respiratory system should be closely monitored as early identification of problems may allow better insight into the immediate prognosis.
呼吸系统衰竭是肌萎缩侧索硬化症最常见的死亡原因。这是由于呼吸肌肉组织减弱导致呼吸衰竭、咳嗽无力以及无法防止肺部误吸。目前治疗仅为支持性治疗，但负压或正压机械通气提供了一些延长生命的可能性。呼吸系统应密切监测，因为早期发现问题可能有助于更好地洞察近期预后。
