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A chromosome-level genome of the human blood fluke Schistosoma japonicum identifies the genomic basis of host-switching.日本血吸虫染色体水平基因组揭示了宿主转换的基因组基础。
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A metalloprotease produced by larval Schistosoma mansoni facilitates infection establishment and maintenance in the snail host by interfering with immune cell function.曼氏血吸虫幼虫产生的一种金属蛋白酶通过干扰免疫细胞功能促进在螺宿主中感染的建立和维持。
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3
Identification and characterization of six novel tetraspanins from Schistosoma japonicum.鉴定和分析日本血吸虫中的六个新的四跨膜蛋白。
Parasit Vectors. 2011 Sep 29;4:190. doi: 10.1186/1756-3305-4-190.
4
Population differentiation as a test for selective sweeps.种群分化作为选择清除的检验。
Genome Res. 2010 Mar;20(3):393-402. doi: 10.1101/gr.100545.109. Epub 2010 Jan 19.
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The history of schistosomiasis japonica in Taiwan.台湾日本血吸虫病的历史。
Kaohsiung J Med Sci. 2006 Jul;22(7):309-20. doi: 10.1016/S1607-551X(09)70317-1.
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Biological characteristics and control of intermediate snail host of Schistosoma japonicum.日本血吸虫中间宿主螺类的生物学特性与防治
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7
Detecting recent positive selection in the human genome from haplotype structure.从单倍型结构检测人类基因组中近期的正选择。
Nature. 2002 Oct 24;419(6909):832-7. doi: 10.1038/nature01140. Epub 2002 Oct 9.
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Strain complex of Schistosoma japonicum in the mainland of China.中国大陆日本血吸虫的虫株复合体
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Schistosoma japonicum: the pathology of experimental infection.日本血吸虫:实验性感染的病理学
Exp Parasitol. 1985 Feb;59(1):1-11. doi: 10.1016/0014-4894(85)90051-7.

一个关于血吸虫宿主特异性的基因组难题。

A genomic can of worms for schistosome host-specificity.

机构信息

Department of Biology, University of Texas at Arlington, Arlington, TX 76019, USA.

Department of Environmental and Occupational Health, Colorado School of Public Health, University of Colorado Anschutz, Aurora, CO 80045, USA.

出版信息

Trends Parasitol. 2022 Jul;38(7):496-497. doi: 10.1016/j.pt.2022.04.005. Epub 2022 May 1.

DOI:10.1016/j.pt.2022.04.005
PMID:35504822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9450497/
Abstract

Understanding the genetic underpinnings of schistosome host preferences is critical. Luo et al. recently identified genes associated with intermediate and definitive host-switching based on a new chromosome-level genome for Schistosoma japonicum, population genetic comparisons, and follow-up experiments. This represents a guide to fully map-selected schistosome genes using population genetics.

摘要

了解血吸虫宿主偏好的遗传基础至关重要。罗等人最近基于日本血吸虫的新染色体水平基因组、群体遗传比较和后续实验,确定了与中间宿主和终宿主转换相关的基因。这代表了使用群体遗传学全面绘制选定血吸虫基因图谱的指南。