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所有患者分期入院与一期入院行腹腔镜胆囊切除术和胆管探查术的发病率、手术难度和结局:回顾 5750 例患者。

The incidence, operative difficulty and outcomes of staged versus index admission laparoscopic cholecystectomy and bile duct exploration for all comers: a review of 5750 patients.

机构信息

Laparoscopic Biliary Service, University Hospital Monklands, Monkscourt Avenue, Airdrie, Lanarkshire, ML6 0JS, Scotland, UK.

出版信息

Surg Endosc. 2022 Nov;36(11):8221-8230. doi: 10.1007/s00464-022-09272-0. Epub 2022 May 4.

Abstract

BACKGROUND

The timing of laparoscopic cholecystectomy (LC) for emergency biliary admissions remains inconsistent with national and international guidelines. The perception that LC is difficult in acute cholecystitis and the popularity of the two-session approach to pancreatitis and suspected choledocholithiasis result in delayed management.

METHODS

Analysis of prospectively maintained data in a unit adopting a policy of "intention to treat" during the index admission. The aim was to study the incidence of previous biliary admissions and compare the operative difficulty, complications and postoperative outcomes with patients who underwent index admission LC.

RESULTS

Of the 5750 LC performed, 20.8% had previous biliary episodes resulting in one admission in 93% and two or more in 7%. Most presented with biliary colic (39.6%) and acute cholecystitis (27.6%). A previous biliary history was associated with increased operative difficulty (p < 0.001), longer operating times (86.9 vs. 68.1 min, p < 0.001), more postoperative complications (7.8% vs. 5.4%, p = 0.002) and longer hospital stay (8.1 vs. 5.5 days, p < 0.001) and presentation to resolution intervals. However, conversion and mortality rates showed no significant differences.

CONCLUSION

Index admission LC is superior to interval cholecystectomy and should be offered to all patients fit for general anaesthesia regardless of the presenting complaints. Subspecialisation should be encouraged as a major factor in optimising resource utilisation and postoperative outcomes of biliary emergencies.

摘要

背景

腹腔镜胆囊切除术(LC)治疗急症胆道疾病的时机仍与国家和国际指南不一致。人们普遍认为急性胆囊炎行 LC 难度大,以及对胰腺炎和疑似胆总管结石采用两阶段治疗的方法,导致治疗延迟。

方法

对采用“意向治疗”策略的一个科室的前瞻性资料进行分析。目的是研究既往胆道疾病发作的发生率,并比较行 LC 治疗的患者的手术难度、并发症和术后结局。

结果

在 5750 例 LC 中,20.8%的患者有既往胆道疾病发作史,其中 93%的患者仅发作 1 次,7%的患者发作 2 次或以上。大多数患者以胆绞痛(39.6%)和急性胆囊炎(27.6%)就诊。既往胆道疾病史与手术难度增加(p<0.001)、手术时间延长(86.9 分钟比 68.1 分钟,p<0.001)、术后并发症增加(7.8%比 5.4%,p=0.002)和住院时间延长(8.1 天比 5.5 天,p<0.001)以及就诊至缓解时间间隔延长有关。然而,中转开腹率和死亡率无显著差异。

结论

对适合全身麻醉的所有患者,行 LC 治疗优于择期胆囊切除术,应将其作为治疗所有适合接受手术的患者的首选方案。鼓励亚专科治疗,这是优化胆道急症资源利用和术后结局的主要因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1702/9613731/628f73fdd605/464_2022_9272_Fig1_HTML.jpg

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