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择期或急诊腹腔镜胆囊切除术和胆管探查术的手术难度、发病率和死亡率与肥胖无关。

Operative Difficulty, Morbidity and Mortality Are Unrelated to Obesity in Elective or Emergency Laparoscopic Cholecystectomy and Bile Duct Exploration.

机构信息

Laparoscopic Upper GI and Biliary Service, University Hospital Monklands, Airdrie, Scotland, UK.

Department of Surgery, Glasgow Royal Infirmary, Glasgow, Scotland, UK.

出版信息

J Gastrointest Surg. 2022 Sep;26(9):1863-1872. doi: 10.1007/s11605-022-05344-7. Epub 2022 May 31.


DOI:10.1007/s11605-022-05344-7
PMID:35641812
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9489587/
Abstract

OBJECTIVES: The challenges posed by laparoscopic cholecystectomy (LC) in obese patients and the methods of overcoming them have been addressed by many studies. However, no objective tool of reporting operative difficulty was used to adjust the outcomes and compare studies. The aim of this study was to establish whether obesity adds to the difficulty of LC and laparoscopic common bile duct exploration (LCBDE) and affects their outcomes on a specialist biliary unit with a high emergency workload. METHODS: A prospectively maintained database of 4699 LCs and LCBDEs performed over 19 years was analysed. Data of patients with body mass index (BMI) ≥ 35, defined as grossly obese, was extracted and compared to a control group. RESULTS: A total of 683 patients (14.5%) had a mean BMI of 39.9 (35-63), of which 63.4% met the definition of morbidly obese. They had significantly more females and significantly higher ASA II classifications. They had equal proportions of emergency admissions, similar incidence of operative difficulty grades 4 or 5 and no open conversions and were less likely to undergo LCBDE than non-obese patients. There were no significant differences in median operative times, morbidity, readmission or mortality rates. CONCLUSIONS: This study, the first to classify gall stone surgery in obese patients according to operative difficulty grading, showed no difference in complexity when compared to the non-obese. Refining access and closure techniques is key to avoiding difficulties. Index admission surgery for biliary emergencies prevents multiple admissions with potential complications and should not be denied due to obesity.

摘要

目的:腹腔镜胆囊切除术 (LC) 在肥胖患者中面临的挑战以及克服这些挑战的方法已经在许多研究中得到了探讨。然而,目前还没有用于报告手术难度的客观工具来调整结果并比较研究。本研究旨在确定肥胖是否会增加 LC 和腹腔镜胆总管探查术 (LCBDE) 的难度,并对在一个高急诊工作量的专业胆道单位的手术结果产生影响。

方法:对 19 年来行 4699 例 LC 和 LCBDE 的前瞻性维护数据库进行了分析。提取并比较了体重指数 (BMI)≥35 定义为肥胖患者的患者数据与对照组。

结果:共有 683 例患者(14.5%)的 BMI 平均值为 39.9(35-63),其中 63.4%符合病态肥胖的定义。肥胖患者中女性明显更多,ASA II 分级明显更高。急诊入院比例相等,手术难度 4 级或 5 级的发生率相似,无中转开放手术,与非肥胖患者相比,LCBDE 的比例较低。中位手术时间、发病率、再入院率或死亡率无显著差异。

结论:本研究首次根据手术难度分级对肥胖患者的胆囊结石手术进行分类,与非肥胖患者相比,手术复杂性无差异。完善入路和关闭技术是避免困难的关键。胆道急症的指数入院手术可避免多次潜在并发症的入院,不应因肥胖而被拒绝。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0da8/9489587/9e03e3652ede/11605_2022_5344_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0da8/9489587/aeebd80b48af/11605_2022_5344_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0da8/9489587/9e03e3652ede/11605_2022_5344_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0da8/9489587/aeebd80b48af/11605_2022_5344_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0da8/9489587/9e03e3652ede/11605_2022_5344_Fig2_HTML.jpg

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[1]
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[2]
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[3]
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[4]
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Cureus. 2024-10-28

[5]
The Influence of Obesity on Cholecystectomy Outcomes: A Systematic Review of Laparoscopic and Open Approaches.

Cureus. 2024-8-5

本文引用的文献

[1]
The obesity paradox: Underweight patients are at the greatest risk of mortality after cholecystectomy.

Surgery. 2021-9

[2]
Obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitis.

Sci Rep. 2021-1-27

[3]
Achieving the critical view of safety in the difficult laparoscopic cholecystectomy: a prospective study of predictors of failure.

Surg Endosc. 2021-11

[4]
Optimising the outcomes of index admission laparoscopic cholecystectomy and bile duct exploration for biliary emergencies: a service model.

Surg Endosc. 2021-8

[5]
Impact of obesity and metabolic health status in the development of non-alcoholic fatty liver disease (NAFLD): A United Kingdom population-based cohort study using the health improvement network (THIN).

BMC Endocr Disord. 2020-6-30

[6]
Characteristics of Trocar Site Hernia after Laparoscopic Cholecystectomy.

Sci Rep. 2020-2-18

[7]
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Surg Endosc. 2018-6-28

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A randomised, single blinded trial, assessing the effect of a two week preoperative very low calorie diet on laparoscopic cholecystectomy in obese patients.

HPB (Oxford). 2016-5

[9]
Day case laparoscopic cholecystectomy in patients with high BMI: Experience from a UK centre.

Ann R Coll Surg Engl. 2016-5

[10]
Laparoscopy decreases complications for obese patients undergoing elective rectal surgery.

Surg Endosc. 2016-5

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