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Bulsufan decreases the incidence of mixed chimaerism in HLA-matched donor transplantation for severe aplastic anaemia.

作者信息

Xu Lan-Ping, Xu Zheng-Li, Zhang Yuan-Yuan, Cheng Yi-Fei, Mo Xiao-Dong, Han Ting-Ting, Wang Feng-Rong, Yan Chen-Hua, Sun Yu-Qian, Chen Yu-Hong, Tang Fei-Fei, Han Wei, Wang Yu, Zhang Xiao-Hui, Liu Kai-Yan, Huang Xiao-Jun

机构信息

Peking University People's Hospital, Peking University Institute of Hematology, Beijing, China.

National Clinical Research Center for Hematologic Disease, Beijing, China.

出版信息

Bone Marrow Transplant. 2022 Jul;57(7):1204-1206. doi: 10.1038/s41409-022-01682-x. Epub 2022 May 4.

DOI:10.1038/s41409-022-01682-x
PMID:35508709
Abstract
摘要

相似文献

1
Bulsufan decreases the incidence of mixed chimaerism in HLA-matched donor transplantation for severe aplastic anaemia.白消安可降低 HLA 配型相合供者移植治疗重型再生障碍性贫血时混合嵌合体的发生率。
Bone Marrow Transplant. 2022 Jul;57(7):1204-1206. doi: 10.1038/s41409-022-01682-x. Epub 2022 May 4.
2
Mixed chimaerism is associated with poorer long-term failure-free survival among aplastic anaemia patients receiving HLA-matched donor transplantation.混合嵌合体与接受HLA匹配供体移植的再生障碍性贫血患者较差的长期无失败生存率相关。
Bone Marrow Transplant. 2023 Jul;58(7):832-834. doi: 10.1038/s41409-023-01974-w. Epub 2023 Apr 11.
3
Campath-1G in vivo confers a low incidence of graft-versus-host disease associated with a high incidence of mixed chimaerism after bone marrow transplantation for severe aplastic anaemia using HLA-identical sibling donors.在使用 HLA 全相合同胞供者对重型再生障碍性贫血进行骨髓移植后，体内注射 Campath-1G 可使移植物抗宿主病的发生率较低，同时混合嵌合体的发生率较高。
Bone Marrow Transplant. 1996 May;17(5):819-24.
4
Effect of mixed chimerism on graft-versus-host disease, disease recurrence and survival after HLA-identical marrow transplantation for aplastic anemia or chronic myelogenous leukemia.混合嵌合体对再生障碍性贫血或慢性粒细胞白血病患者接受 HLA 全相合骨髓移植后移植物抗宿主病、疾病复发及生存的影响。
Bone Marrow Transplant. 1996 Oct;18(4):767-76.
5
Bone marrow transplantation for acquired severe aplastic anemia.获得性重型再生障碍性贫血的骨髓移植
Hematol Oncol Clin North Am. 2014 Dec;28(6):1145-55. doi: 10.1016/j.hoc.2014.08.004. Epub 2014 Oct 5.
6
Allogeneic unrelated bone marrow transplantation from older donors results in worse prognosis in recipients with aplastic anemia.来自老年供者的异基因非血缘骨髓移植会导致再生障碍性贫血受者的预后更差。
Haematologica. 2016 May;101(5):644-52. doi: 10.3324/haematol.2015.139469. Epub 2016 Feb 8.
7
Leukaemic transformation of donor cells in a patient receiving a second allogeneic bone marrow transplant for severe aplastic anaemia.一名接受第二次异基因骨髓移植治疗严重再生障碍性贫血的患者中供体细胞的白血病转化。
Bone Marrow Transplant. 2002 Mar;29(5):453-6. doi: 10.1038/sj.bmt.1703372.
8
Graft failure and severe autoimmune haemolysis following fludarabine-based reduced-intensity matched unrelated donor bone marrow transplantation for severe aplastic anaemia: salvage by second transplant with conventional dose conditioning.氟达拉滨为基础的低强度匹配无关供者骨髓移植治疗重型再生障碍性贫血后发生移植物失败和严重自身免疫性溶血：采用传统剂量预处理进行二次移植挽救治疗
Bone Marrow Transplant. 2006 Aug;38(4):317-8. doi: 10.1038/sj.bmt.1705433. Epub 2006 Jul 3.
9
Marrow transplant experience for children with severe aplastic anemia.重度再生障碍性贫血患儿的骨髓移植经验
Am J Pediatr Hematol Oncol. 1994 Feb;16(1):43-9.
10
Treatment of aplastic anemia.再生障碍性贫血的治疗。
Hematol Oncol Clin North Am. 1990 Jun;4(3):559-75.

引用本文的文献

1
Conditioning Regimen Options.预处理方案选项
Adv Exp Med Biol. 2025;1475:41-55. doi: 10.1007/978-3-031-84988-6_3.
2
Time-dependent analysis of the impact on early cytomegalovirus reactivation of HLA mismatch and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation from related donors in acquired aplastic anemia.获得性再生障碍性贫血患者接受亲缘供者异基因造血细胞移植后，HLA 错配和急性移植物抗宿主病对早期巨细胞病毒再激活影响的时间依赖性分析。
Ann Hematol. 2023 Sep;102(9):2589-2598. doi: 10.1007/s00277-023-05332-0. Epub 2023 Jul 13.
3
Low-dose post-transplant cyclophosphamide with G-CSF/ATG based haploidentical protocol provides favorable outcomes for SAA patients.

本文引用的文献

1
Optimizing conditioning regimen with low-dose irradiation or busulfan enables the outcome of transplantation from a 6-7/8 HLA-matched donor comparable to that from an 8/8 HLA-matched unrelated donor in severe aplastic anemia patients under 40 years.在 40 岁以下重型再生障碍性贫血患者中，通过低剂量照射或白消安预处理的优化调节方案，6-7/8 HLA 匹配供者移植的结果可与 8/8 HLA 匹配无关供者移植的结果相媲美。
Ann Hematol. 2021 Sep;100(9):2363-2373. doi: 10.1007/s00277-021-04540-w. Epub 2021 May 14.
2
Choice of conditioning regimens for bone marrow transplantation in severe aplastic anemia.重型再生障碍性贫血骨髓移植时的预处理方案选择。
Blood Adv. 2019 Oct 22;3(20):3123-3131. doi: 10.1182/bloodadvances.2019000722.
3
低剂量移植后环磷酰胺联合 G-CSF/ATG 的单倍体相合方案为 SAA 患者提供了良好的结局。
Front Immunol. 2023 May 10;14:1173320. doi: 10.3389/fimmu.2023.1173320. eCollection 2023.
Aplastic Anemia.
再生障碍性贫血
N Engl J Med. 2018 Oct 25;379(17):1643-1656. doi: 10.1056/NEJMra1413485.
4
Severe aplastic anemia: allogeneic bone marrow transplantation as first-line treatment.重型再生障碍性贫血：异基因骨髓移植作为一线治疗。
Blood Adv. 2018 Aug 14;2(15):2020-2028. doi: 10.1182/bloodadvances.2018021162.
5
Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis.白消安暴露与儿童及青年造血细胞移植后的生存及毒性的关联：一项多中心回顾性队列分析
Lancet Haematol. 2016 Nov;3(11):e526-e536. doi: 10.1016/S2352-3026(16)30114-4. Epub 2016 Oct 13.