Linggood M A, Porter P
Immunology. 1978 Jul;35(1):125-7.
The heat labile K88 antigen which is a product of an episomal gene, was eliminated from a pocrine enteropathogen by passage through media containing sow colostrum antibodies raised against heart stable antigens of E. coli. In consequence the porcine enteropathogen lost its ability to adhere to and aggluinate chicken erythrocytes, and model system for piglet intestinal adhesion and virulence.
热不稳定的K88抗原是一种附加体基因的产物,通过在含有针对大肠杆菌心脏稳定抗原产生的母猪初乳抗体的培养基中传代,从一种分泌型肠道病原体中被去除。结果,这种猪肠道病原体失去了黏附并凝集鸡红细胞的能力,以及仔猪肠道黏附和毒力的模型系统。