Department of ENT, Sheffield Teaching Hospitals Foundation Trust, Sheffield, UK.
J Laryngol Otol. 2022 Oct;136(10):998-1001. doi: 10.1017/S0022215121003480. Epub 2022 May 6.
The presentation of unilateral nasal polyps traditionally necessitates histological evaluation for a neoplasm. This study sought to determine the rates of significant pathology in patients presenting with benign-appearing unilateral nasal polyps, to inform practice.
All patients who underwent nasal polypectomy for benign-appearing unilateral nasal polyps over a 13-year period were included.
A total of 77 patients were included. On histology, 60 cases (77.9 per cent) were found to be inflammatory polyps. Thirteen cases were neoplastic, of which 11 (14.3 per cent) were benign and 2 (2.6 per cent) were malignant neoplasms. The following significant pathologies were found: Schneiderian papillomas, in 10 cases (13.0 per cent); neurofibroma, in 1 case (1.3 per cent); adenoid cystic carcinoma, in 1 case (1.3 per cent); and malignant melanoma, in 1 case (1.3 per cent).
Our data support routine histological assessment for all unilateral nasal polyps. Malignancy is rare (2.6 per cent) in patients presenting with benign-appearing unilateral nasal polyps. In elderly, unfit patients with minimal symptoms, initial conservative management may be reasonable.
单侧鼻息肉的表现传统上需要进行组织学评估以排除肿瘤。本研究旨在确定表现为良性单侧鼻息肉的患者中出现显著病理的比例，以为临床实践提供依据。
纳入了在 13 年期间因良性单侧鼻息肉而行鼻息肉切除术的所有患者。
共纳入 77 例患者。组织学检查发现，60 例（77.9%）为炎性息肉。13 例为肿瘤，其中 11 例（14.3%）为良性肿瘤，2 例（2.6%）为恶性肿瘤。发现了以下显著病变：10 例（13.0%）为嗅神经鞘瘤；1 例（1.3%）为神经纤维瘤；1 例（1.3%）为腺样囊性癌；1 例（1.3%）为恶性黑色素瘤。
我们的数据支持对所有单侧鼻息肉进行常规组织学评估。表现为良性单侧鼻息肉的患者中恶性肿瘤罕见（2.6%）。对于症状轻微且身体状况不佳的老年患者，初始保守治疗可能是合理的。
