Yoon Joo-Heon, Kim Chang-Hoon, Choi Eun Chang
Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea.
J Laryngol Otol. 2002 Sep;116(9):699-702. doi: 10.1258/002221502760237984.
This series was undertaken to investigate the incidence of associated polyps and the recurrence rates of inverted papillomas with, or without, malignancies, as well as the treatment outcomes of the recurred cases. A retrospective study evaluating the pathology, associated polyps, types of operation, recurrence rate after original operation, and surgical outcomes of recurred cases was conducted upon 96 patients diagnosed with inverted papilloma. The overall malignancy rate was 11.5 per cent with synchronous tumours accounting for 9.4 per cent and metachronous for 2.1 per cent. Inflammatory polyps were found in association with inverted papilloma in 21.9 per cent. In cases without malignancies, the recurrence rate after the original conservative procedure was 33.9 per cent, compared to 14.3 per cent after a medial maxillectomy. In cases with malignancies, the recurrence rate after the original surgical procedure was 22.2 per cent. Our study indicates that more aggressive and bolder surgical resection of inverted papilloma should be undertaken as a primary treatment method, or as a treatment for recurrent cases to reduce the recurrence rate of inverted papilloma with, or without, malignancy.
本系列研究旨在调查伴发息肉的发生率、有无恶性肿瘤的内翻性乳头状瘤的复发率，以及复发病例的治疗结果。对96例诊断为内翻性乳头状瘤的患者进行了一项回顾性研究，评估其病理、伴发息肉、手术类型、初次手术后的复发率以及复发病例的手术结果。总体恶性率为11.5%，同时性肿瘤占9.4%，异时性肿瘤占2.1%。21.9%的内翻性乳头状瘤患者伴有炎性息肉。在无恶性肿瘤的病例中，初次保守手术后的复发率为33.9%，而在上颌骨内侧切除术后为14.3%。在有恶性肿瘤的病例中，初次手术后的复发率为22.2%。我们的研究表明，应采取更积极大胆的手术切除作为内翻性乳头状瘤的主要治疗方法，或作为复发病例的治疗方法，以降低有无恶性肿瘤的内翻性乳头状瘤的复发率。
