From the Department of Ophthalmology, Shaare Zedek Medical Center, Jerusalem, Israel, affiliated to the Hebrew University, Jerusalem, Israel.
J Cataract Refract Surg. 2022 Nov 1;48(11):1248-1252. doi: 10.1097/j.jcrs.0000000000000964.
To evaluate the effect of pharmacologic pupil dilation on the quality of axial length (AL) measurement in patients with dense cataracts and previous low-quality AL measurements performed without dilation.
Shaare-Zedek Medical Center, Jerusalem, Israel.
Retrospective case series.
All participants underwent swept-source optical coherence tomographic (SS-OCT) biometry. Those with low-quality AL measurements due to dense cataract underwent an additional SS-OCT biometric evaluation after pupil dilation, and the AL measurement of the same eye was recorded.
2076 patients underwent SS-OCT during the study period, and 177 (8.52%) had low-quality AL measurements because of dense cataract. 79 (44.63%, mean age 72.53 ± 13.27 years, 43 females) of those 177 patients underwent repeat SS-OCT biometric imaging after pharmacologic pupil dilation, and formed the study group. After pupil dilation, high-quality AL measurements were successfully obtained in 60 (75.95%) of the 79 eyes. The mean SD of the AL measurements decreased significantly ( P < .001), and the number of successful OCT scans per measurement increased significantly ( P < .001) after pupil dilation. The mean difference of the AL before and after pupil dilation was 0.03 ± 0.07 mm ( P < .001).
Pharmacologic pupil dilation improved the quality of SS-OCT biometrically measured AL in patients with low-quality AL measurement due to dense cataract. These results could potentially improve postoperative refractive outcomes after cataract surgery and reduce the need of additional AL measurements by more complicated alternative means in this group.
评估药物性瞳孔散大对白内障密度高且既往未经散瞳的低质量眼轴(AL)测量患者的 AL 测量质量的影响。
以色列耶路撒冷的 Shaare-Zedek 医疗中心。
回顾性病例系列。
所有参与者均接受扫频源光学相干断层扫描(SS-OCT)生物测量。由于白内障密度高而导致 AL 测量质量低的患者,在瞳孔散大后进行额外的 SS-OCT 生物测量评估,并记录同眼的 AL 测量值。
在研究期间,2076 例患者接受了 SS-OCT 检查,其中 177 例(8.52%)因白内障密度高而导致 AL 测量质量低。在这 177 例患者中,有 79 例(44.63%,平均年龄 72.53 ± 13.27 岁,43 例女性)接受了药物性瞳孔散大后的重复 SS-OCT 生物测量成像,形成了研究组。瞳孔散大后,60 只(75.95%)眼中成功获得了高质量的 AL 测量值。瞳孔散大后,AL 测量值的均方根显著降低(P <.001),每次测量成功的 OCT 扫描次数显著增加(P <.001)。瞳孔散大前后 AL 的平均差值为 0.03 ± 0.07 mm(P <.001)。
药物性瞳孔散大改善了白内障密度高且既往未经散瞳的低质量 AL 测量患者的 SS-OCT 生物测量 AL 质量。这些结果可能会改善白内障手术后的屈光效果,并减少这组患者通过更复杂的替代方法进行额外 AL 测量的需求。