Tañá-Rivero Pedro, Aguilar-Córcoles Salvador, Tañá-Sanz Pedro, Tañá-Sanz Santiago, Montés-Micó Robert
Oftalvist, C/Angel Lozano 11, 03001, Alicante, Spain.
Optics and Optometry and Vision Sciences Department, University of Valencia, Valencia, Spain.
Eye Vis (Lond). 2023 Sep 1;10(1):35. doi: 10.1186/s40662-023-00352-3.
To evaluate the axial length acquisition success rates and agreement between various biometric parameters obtained with different biometers in dense cataracts.
Fifty-one eyes were measured using Anterion®, Argos® and IOLMaster® 700 swept-source optical coherence tomography (SS-OCT) biometers, a Pentacam® AXL partial coherence interferometry (PCI) biometer, and an OcuScan® RxP ultrasound biometer. We measured keratometry (K1, flattest keratometry and K2, steepest keratometry), white-to-white (WTW), anterior chamber depth (ACD), lens thickness (LT) and axial length. Cataracts were classified according to the Lens Opacities Classification System III grading system, the dysfunctional lens index (DLI) and Pentacam® nucleus staging (PNS) metrics. Percentage of acquisition success rate and a Bland-Altman analysis for the agreement between biometers were calculated.
The mean LOCS III score was 3.63 ± 0.92, the mean DLI was 2.95 ± 1.30 and the mean PNS was 2.36 ± 1.20. The acquisition success rates for the Anterion®, Argos®, IOLMaster® 700, Pentacam® AXL and OcuScan® RxP biometers were 94.12%, 100%, 98.04%, 60.78% and 100%, respectively. There were significant differences in the success rates between biometers (P = 0.014). There were statistically significant differences between biometers for all parameters evaluated (P < 0.05). The range of the limit of agreement (LoA) for all comparisons of K1 and K2 were > 1.00 D. The LoA for WTW ranged from 0.095 to 1.050 mm. The LoA for ACD and LT ranged from 0.307 to 0.114 mm and from 0.378 to 0.108 mm, respectively. The LoA for axial length ranged from 0.129 to 2.378 mm.
Among optical biometers, those based on SS-OCT technology are more successful at measuring axial length in eyes with dense cataracts.
The study was registered with the National Institutes of Health (clinical trial identifier NCT05239715, http://www.
gov ).
评估在致密性白内障中使用不同生物测量仪获取眼轴长度的成功率以及各种生物测量参数之间的一致性。
使用Anterion®、Argos®和IOLMaster® 700扫频光学相干断层扫描（SS-OCT）生物测量仪、Pentacam® AXL部分相干干涉测量（PCI）生物测量仪以及OcuScan® RxP超声生物测量仪对51只眼进行测量。我们测量了角膜曲率（K1，最平角膜曲率；K2，最陡角膜曲率）、白到白（WTW）、前房深度（ACD）、晶状体厚度（LT）和眼轴长度。根据晶状体混浊分类系统III分级系统、晶状体功能障碍指数（DLI）和Pentacam®晶状体核分期（PNS）指标对白内障进行分类。计算获取成功率的百分比以及生物测量仪之间一致性的Bland-Altman分析。
平均LOCS III评分为3.63±0.92，平均DLI为2.95±1.30，平均PNS为2.36±1.20。Anterion®、Argos®、IOLMaster® 700、Pentacam® AXL和OcuScan® RxP生物测量仪的获取成功率分别为94.12%、100%、98.04%、60.78%和100%。生物测量仪之间的成功率存在显著差异（P = 0.014）。在所有评估参数方面，生物测量仪之间存在统计学显著差异（P < 0.05）。K1和K2所有比较的一致性界限（LoA）范围均>1.00 D。WTW的LoA范围为0.095至1.050 mm。ACD和LT的LoA范围分别为0.307至0.114 mm和0.378至0.108 mm。眼轴长度的LoA范围为0.129至2.378 mm。
在光学生物测量仪中，基于SS-OCT技术的仪器在测量致密性白内障眼的眼轴长度方面更成功。
该研究已在美国国立卫生研究院注册（临床试验标识符NCT05239715，http://www.CLINICALTRIALS.gov）
