Liu Zengchen, Li Shujing, Ge Genwu, Li Yanxia, Zhao Chunxiang, Zhang Hui, Yang Zhiguang
College of Chemistry and Chemical Engineering, Henan Key Laboratory of Rare Earth Functional Materials, International Joint Research Laboratory for Biomedical Nanomaterials of Henan, The Key Laboratory of Rare Earth Functional Materials and Applications, Zhoukou Normal University Zhoukou 466001 PR China
RSC Adv. 2019 Feb 12;9(10):5377-5383. doi: 10.1039/c8ra10036e. eCollection 2019 Feb 11.
In the study, a highly selective and sensitive fluorescence sensor derived from nitrogen heterocycle was synthesized and characterized. By the fluorescence experiments, it was found to show a higher response toward Al than other commonly coexistent metal ions in CHOH/HO media (pH = 7.2). Moreover, the large binding constant (3.44 × 10 M) between Al and the sensor was calculated by fluorescence titration experiment. In addition, the synergistic effect mechanism due to photoinduced electron transfer (PET) and C[double bond, length as m-dash]N isomerization was deduced according to the fluorescence behavior. In addition, the fluorescence imaging in living cells was studied systemically, which exhibited high fluorescence sensing activity toward Al.
在该研究中，合成并表征了一种源自氮杂环的高选择性和灵敏荧光传感器。通过荧光实验发现，在CHOH/HO介质（pH = 7.2）中，该传感器对铝的响应高于其他常见共存金属离子。此外，通过荧光滴定实验计算出铝与该传感器之间的大结合常数（3.44×10 M）。另外，根据荧光行为推导了光诱导电子转移（PET）和C[双键，长度为m破折号]N异构化引起的协同效应机制。此外，还系统研究了活细胞中的荧光成像，其对铝表现出高荧光传感活性。
