Liu Z C, Zhu W P, Chen Y H, Li Y X, Ding Y J, Yang W J, Li K
College of Chemistry and Chemical Engineering, The Key Laboratory of Rare Earth Functional Materials and Applications, Zhoukou Normal University, Zhoukou 466001, PR China.
Dalton Trans. 2015 Oct 7;44(37):16528-33. doi: 10.1039/c5dt02220g.
In this paper, a simple small molecule (L) based on 4-(diethylamino)-2-hydroxy-benzaldehyde and carbohydrazide has been synthesized and characterized. Moreover, under ultrasonic conditions, a host-guest system with β-cyclodextrin and L was obtained. According to the hybridization process, the host-guest system showed excellent water solubility. The investigation of the fluorescence spectra revealed that the host-guest system exhibited a characteristic fluorescence behavior toward Al(3+) in a pure water environment. Upon addition of Al(3+), the host-guest system showed a strong blue fluorescence, which resulted from the fluorophore of L after the coordination of β-CD-L and Al(3+) with a high binding constant (k = 3.1626 × 10(11) M(-1)). In addition, SEM images demonstrated that the host-guest system expressed good crystallization behavior. Fluorescence microscope images of onion epidermal cells with β-CD-L-Al(3+) proved that the water-soluble host-guest system possessed a high ability for cell permeability.
本文合成并表征了一种基于4-(二乙氨基)-2-羟基苯甲醛和 carbohydrazide 的简单小分子（L）。此外，在超声条件下，获得了一种由β-环糊精和L组成的主客体体系。根据杂交过程，该主客体体系表现出优异的水溶性。荧光光谱研究表明，在纯水环境中，该主客体体系对Al(3+)呈现出特征荧光行为。加入Al(3+)后，主客体体系发出强烈的蓝色荧光，这是由于β-CD-L与Al(3+)配位后L的荧光团产生的，结合常数较高（k = 3.1626 × 10(11) M(-1)）。此外，扫描电子显微镜图像表明主客体体系具有良好的结晶行为。β-CD-L-Al(3+)处理的洋葱表皮细胞的荧光显微镜图像证明，水溶性主客体体系具有较高的细胞通透性。
