具有肽靶向能力的近红外发光镧系（III）配合物作为光学成像剂的原型：一种方法学途径。
Near-infrared emitting lanthanide(iii) complexes as prototypes of optical imaging agents with peptide targeting ability: a methodological approach.
作者信息
Cieslikiewicz-Bouet Monika, Eliseeva Svetlana V, Aucagne Vincent, Delmas Agnès F, Gillaizeau Isabelle, Petoud Stéphane
机构信息
Institut de Chimie Organique et Analytique, UMR CNRS 7311, Université d'Orléans rue de Chartres 45100 Orléans France
Centre de Biophysique Moléculaire, CNRS UPR 4301 rue Charles Sadron 45071 Orléans Cedex 2 France
出版信息
RSC Adv. 2019 Jan 14;9(3):1747-1751. doi: 10.1039/c8ra09419e. eCollection 2019 Jan 9.
A methodological approach to design prototypes of specific near-infrared emitting imaging agents based on a small molecular compound combining a lanthanide(iii) ion, the cyclen derivative as a coordinating unit and the azo-dye as a sensitizer with a Arg-Gly-Asp cyclopeptide as a targeting moiety, is presented here.
本文提出了一种方法，用于设计基于小分子化合物的特定近红外发光成像剂的原型，该小分子化合物将镧系（III）离子、作为配位单元的环烯衍生物、作为敏化剂的偶氮染料与作为靶向部分的精氨酸-甘氨酸-天冬氨酸环肽相结合。
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