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尼日利亚阿布贾的年轻人中的 HIV 感染和中风:病例系列。

HIV infection and stroke in the Young in Abuja, Nigeria: a case series.

机构信息

Department of Internal Medicine, Faculty of Clinical Sciences, College of Health Sciences, Nile University of Nigeria, Asokoro District Hospital, Abuja, Nigeria.

Department of Surgery, Faculty of Clinical Sciences, College of Health Sciences, Nile University of Nigeria, Asokoro Hospital, Abuja, Nigeria.

出版信息

Pan Afr Med J. 2022 Feb 16;41:132. doi: 10.11604/pamj.2022.41.132.31270. eCollection 2022.

DOI:10.11604/pamj.2022.41.132.31270
PMID:35519168
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9034561/
Abstract

Stroke is a major cause of disability and mortality among the Nigerian general population and thought to be commoner after the fifth decade of life and usually driven by conventional risk factors which are mainly cardio metabolic. However, with the youthful population in a city such as Abuja, stroke could be a mode of presentation of HIV in young people who are also more sexually active. Methods. This is a case series, reporting four cases of HIV positive young Nigerians with stroke. Patients´ data were retrieved from ward admissions records. The patients here had their socio-demographic data taken. They had presented with documented varied clinical features including those suggestive of stroke, after which they had HIV screening done which returned positive. One thousand four hundred and eighty-seven (1487) patients, were admitted in the medical ward, over a three-year period. Female to male ratio of 1:1 in the HIV-positive group, with an age range of 32 to 42 years and an average age of 37.5 years. Stroke constituted 5.7% of all admissions, with stroke in the young accounting for 1.2%. Of all stroke cases, stroke in the young constituted 21.43%, with those who were HIV positive accounting for 4.8%. Young people with stroke should be offered an HIV screening test.

摘要

中风是尼日利亚普通人群残疾和死亡的主要原因,据认为,该病在 50 岁以后更为常见,通常由主要为心血管代谢的传统危险因素驱动。然而,在像阿布贾这样的城市中,年轻人的人口众多,中风可能是年轻的 HIV 感染者的一种表现形式,这些人也更加活跃。

方法。这是一个病例系列报告,介绍了 4 例 HIV 阳性的尼日利亚年轻人中风病例。患者的数据从病房入院记录中检索。这些患者的社会人口统计学数据被采集。他们表现出不同的临床特征,包括那些提示中风的特征,之后进行了 HIV 筛查,结果呈阳性。在三年期间,有 1487 名患者在医疗病房住院。在 HIV 阳性组中,男女比例为 1:1,年龄范围为 32 至 42 岁,平均年龄为 37.5 岁。中风占所有入院人数的 5.7%,年轻人中风占 1.2%。在所有中风病例中,年轻人中风占 21.43%,其中 HIV 阳性者占 4.8%。应向有中风的年轻人提供 HIV 筛查测试。

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Incidence of stroke in patients with HIV infection: A population-based study in Taiwan.台湾地区基于人群的 HIV 感染患者中风发病率研究。
PLoS One. 2019 May 22;14(5):e0217147. doi: 10.1371/journal.pone.0217147. eCollection 2019.
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Stroke in Human Immunodeficiency Virus-infected Individuals in Sub-Saharan Africa (SSA): A Systematic Review.撒哈拉以南非洲地区感染人类免疫缺陷病毒个体的中风:一项系统评价
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Stroke. 2018 May;49(5):1116-1122. doi: 10.1161/STROKEAHA.118.020783. Epub 2018 Apr 4.
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The Role of Human Immunodeficiency Virus-Associated Vasculopathy in the Etiology of Stroke.人类免疫缺陷病毒相关性血管病变在中风病因学中的作用。
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