Usman Muhammad, Guo Xin, Wu Qiusheng, Barman Jitesh, Su Shaoqiang, Huang Bingru, Biao Tang, Zhang Zhang, Zhan Qiuqiang
Centre for Optical and Electromagnetic Research, Guangdong Provincial Key Laboratory of Optical Information Materials and Technology, South China Academy of Advanced Optoelectronics, South China Normal University 510006 Guangzhou China
Electronic Paper Display Institute, South China Academy of Advanced Optoelectronics, South China Normal University 510006 Guangzhou China.
RSC Adv. 2019 May 7;9(25):14109-14115. doi: 10.1039/c9ra00817a.
Surface-enhanced Raman scattering (SERS) technique has emerged as a potentially powerful tool for the detection of trace amounts of environmental contamination and pollutants such as various antibiotics and their active metabolites in the surface aquatic ecosystem (drinking water). In this study, we report the detection method for ciprofloxacin and norfloxacin analytes, two largely used antibiotics in the world, at a very low detection concentration based on the enrichment and efficient delivery of analytes after the evaporation of the solvent on slippery-SERS substrates. The slippery-SERS substrates were fabricated in a very efficient and cost effective way by simply spin-coating the silicone oil onto the widely used glass slides followed by annealing. The analyte particles with gold nanorods (GNRs) were efficiently delivered to the active site by evaporating the aqueous solvent on the slippery surface the suppression of the coffee ring effect caused by the smooth contraction motion of the base contact radius of the droplet without any pinning. Thus, the detection limits of ciprofloxacin and norfloxacin analytes were reduced to 0.01 ppm, which is the lowest limit of detection achieved by any SERS technique. Finally, this study suggests that the fabricated silicone oil-coated slippery surface and GNRs based combinational approach for the SERS detection technique might be a powerful strategy for the reliable detection of the aqueous pollutant analytes even at very low concentrations.
表面增强拉曼散射（SERS）技术已成为一种潜在的强大工具，可用于检测痕量环境污染和污染物，如地表水生生态系统（饮用水）中的各种抗生素及其活性代谢物。在本研究中，我们报告了基于在光滑SERS基底上溶剂蒸发后分析物的富集和高效传输，对环丙沙星和诺氟沙星这两种世界上广泛使用的抗生素分析物进行极低检测浓度检测的方法。通过简单地将硅油旋涂在广泛使用的载玻片上然后退火，以非常高效且经济有效的方式制备了光滑SERS基底。通过在光滑表面上蒸发水性溶剂，带有金纳米棒（GNRs）的分析物颗粒被有效地传输到活性位点，抑制了由液滴底部接触半径的平滑收缩运动引起的咖啡环效应，且没有任何钉扎现象。因此，环丙沙星和诺氟沙星分析物的检测限降低到了0.01 ppm，这是任何SERS技术所达到的最低检测限。最后，本研究表明，所制备的基于硅油涂层光滑表面和GNRs的SERS检测技术组合方法，可能是一种即使在极低浓度下也能可靠检测水性污染物分析物的强大策略。
