Parmigiani Miriam, Albini Benedetta, Pellegrini Giovanni, Genovesi Marco, De Vita Lorenzo, Pallavicini Piersandro, Dacarro Giacomo, Galinetto Pietro, Taglietti Angelo
Department of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Department of Physics, University of Pavia, Via Bassi 6, 27100 Pavia, Italy.
Nanomaterials (Basel). 2022 Oct 14;12(20):3609. doi: 10.3390/nano12203609.
Surface-enhanced Raman scattering (SERS) is becoming widely used as an analytical tool, and the search for stable and highly responsive SERS substrates able to give ultralow detection of pollutants is a current challenge. In this paper we boosted the SERS response of Gold nanostars (GNS) demonstrating that their coating with a layer of silver having a proper thickness produces a 7-fold increase in SERS signals. Glass supported monolayers of these GNS@Ag were then prepared using simple alcoxyliane chemistry, yielding efficient and reproducible SERS chips, which were tested for the detection of molecules representative of different classes of pollutants. Among them, norfloxacin was detected down to 3 ppb, which is one of the lowest limits of detection obtained with this technique for the analyte.
表面增强拉曼散射（SERS）正作为一种分析工具被广泛应用，而寻找能够实现污染物超低检测的稳定且高响应性的SERS基底是当前面临的一项挑战。在本文中，我们增强了金纳米星（GNS）的SERS响应，证明用一层厚度合适的银对其进行包覆会使SERS信号增强7倍。然后，使用简单的烷氧基化化学方法制备了这些GNS@Ag的玻璃支撑单层膜，得到了高效且可重复的SERS芯片，并对其进行了检测不同类别污染物代表性分子的测试。其中，诺氟沙星的检测限低至3 ppb，这是该技术对该分析物所获得的最低检测限之一。
