Xiao Jing, Ma Yonghao, Wu Xiaofang, Gao Jing, Tang Zilong, Han Li-Biao
Key Laboratory of Theoretical Organic Chemistry and Functional Molecule of Ministry of Education, School of Chemistry and Chemical Engineering, Hunan University of Science and Technology Xiangtan 411201 China.
National Institute of Advanced Industrial Science and Technology (AIST) Tsukuba Ibaraki 305-8565 Japan
RSC Adv. 2019 Jul 18;9(39):22343-22347. doi: 10.1039/c9ra04770k. eCollection 2019 Jul 17.
For the first time, by using HPO/I system, various benzyl chlorides, bromides and iodides were dehalogenated successfully. In the presence of HPO, benzyl halides underwent electrophilic substitution reactions with electron-rich arenes, leading to a broad range of diarylmethanes in good yields. These transformations feature green, cheap reducing reagents and metal-free conditions. A possible mechanism was proposed.
首次通过使用HPO/I体系，各种苄基氯、溴化物和碘化物成功实现了脱卤反应。在HPO存在下，苄基卤与富电子芳烃发生亲电取代反应，以良好的产率生成了多种二芳基甲烷。这些转化具有绿色、廉价的还原剂和无金属条件的特点。提出了一种可能的机理。
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