Serological evidence of possible lyme disease in Greece.

Suggestions that Lyme disease exists in Greece remain controversial and no study to date has definitively identified the presence of a species that infects humans. We examined patients throughout Greece suspected for Lyme disease by enzyme-linked immunosorbent assay (ELISA) and by western blotting for sensu lato species. We found one patient positive for and two patients positive for specific IgG antibodies. Both patients were suffering by neurological manifestations and had never traveled abroad. We provide serological evidence of two autochthonous Lyme disease cases in Greece, possibly caused by .