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基于二氧化钛纳米花的湿度传感器及细胞毒性活性。

TiO nanoflowers based humidity sensor and cytotoxic activity.

作者信息

Shinde Pratik V, Gagare Snehal, Rout Chandra Sekhar, Late Dattatray J

机构信息

Centre for Nano and Material Sciences, Jain Global Campus Jakkasandra, Ramanagaram Bangalore 562112 Karnataka India.

Centre for Nanoscience and Nanotechnology, Amity University Maharashtra Mumbai-Pune Expressway, Bhatan 410206 India

出版信息

RSC Adv. 2020 Aug 10;10(49):29378-29384. doi: 10.1039/d0ra05007e. eCollection 2020 Aug 5.

Abstract

We have systematically investigated the humidity sensing performance and cytotoxic activity of TiO nanoflowers synthesized by hydrothermal method. Our result reveals that TiO nanoflower based sensor devices show good performance at room temperature with a maximum sensitivity of ∼815% along with a response time of ∼143 s and a recovery time of ∼33 s. Our findings also evaluate the cytotoxic effect of TiO nanoflowers on human HepG2 cell lines. The cells are cultured in DMEM medium with varying concentrations of TiO nanoflowers for 24, 48 and 72 hours respectively. The results indicate that TiO nanoflower doses time dependently suppress the proliferation of HepG2 cell lines.

摘要

我们系统地研究了通过水热法合成的TiO纳米花的湿度传感性能和细胞毒性活性。我们的结果表明,基于TiO纳米花的传感器器件在室温下表现出良好的性能,最大灵敏度约为815%,响应时间约为143秒,恢复时间约为33秒。我们的研究结果还评估了TiO纳米花对人HepG2细胞系的细胞毒性作用。分别在含有不同浓度TiO纳米花的DMEM培养基中培养细胞24、48和72小时。结果表明,TiO纳米花剂量呈时间依赖性地抑制HepG2细胞系的增殖。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6c1e/9055916/9aa402fefd20/d0ra05007e-f1.jpg

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