Zhang Mengyan, Lian Kaoqi, Ai Lianfeng, Kang Weijun, Zhao Tangjuan
Hebei Key Laboratory of Environment and Human Health, School of Public Health, Hebei Medical University Shijiazhuang 050017 PR China
Technology Center of Shijiazhuang Customs Shijiazhuang 050051 China.
RSC Adv. 2020 Oct 12;10(61):37473-37481. doi: 10.1039/d0ra07064e. eCollection 2020 Oct 7.
With the emergence and spread of coronavirus COVID-19, the use of personal cleansing, medical and household disinfectant products have increased significantly. In this work, a new magnetic solid-phase extraction (MSPE) method for the determination of 11 antiseptic ingredients in surface water by high performance liquid chromatography-mass spectrometry (HPLC-MS/MS) for 6 months based on FeO@PPy magnetic nanoparticles (MNPs) was established. The MSPE method possessed the advantages of simple processing, little time consumption and less organic solvent consumption, and the MNPs could be reused several times. The analytical parameters influencing the extraction efficiency, such as sample pH, amount of MNPs and extraction time, were optimized in detail. It was indicated that the method had satisfactory linearities in the range of 0.50 to 1000.0 μg L with the correlation coefficients () higher than 0.9996. Additionally, satisfactory spiked recoveries were achieved in the range of 80.21-107.33% with relative standard deviations (RSDs) from 1.98% to 8.05%. The limits of detection (LODs) and limits of quantitation (LOQs) were in the range of 0.20 to 2.0 μg L and 0.50 to 5.0 μg L. Therefore, the developed MSPE-HPLC-MS/MS method has high selectivity and stability, and satisfactory quantitative capability for the antiseptic ingredients in surface water. Furthermore, this method can provide relevant technical support for the development of surface water standards.
随着新型冠状病毒COVID-19的出现和传播，个人清洁、医疗和家用消毒产品的使用量显著增加。在这项工作中，基于FeO@PPy磁性纳米颗粒（MNPs）建立了一种新的磁性固相萃取（MSPE）方法，用于通过高效液相色谱-质谱联用（HPLC-MS/MS）测定地表水中的11种防腐剂成分，为期6个月。该MSPE方法具有处理简单、耗时少、有机溶剂消耗少的优点，且MNPs可重复使用多次。详细优化了影响萃取效率的分析参数，如样品pH值、MNPs用量和萃取时间。结果表明，该方法在0.50至1000.0 μg/L范围内具有良好的线性，相关系数（）高于0.9996。此外，加标回收率在80.21-107.33%范围内，相对标准偏差（RSDs）为1.98%至8.05%，令人满意。检测限（LODs）和定量限（LOQs）在0.20至2.0 μg/L和0.50至5.0 μg/L范围内。因此，所建立的MSPE-HPLC-MS/MS方法具有高选择性和稳定性，对地表水中的防腐剂成分具有令人满意的定量能力。此外，该方法可为地表水标准的制定提供相关技术支持。
