Yan Dan, Lu Wei, Qiu Lili, Meng Zihui, Qiao Yu
School of Chemistry and Chemical Engineering, Beijing Institute of Technology Beijing 102488 China
College of Mechanical and Materials Engineering, North China University of Technology Beijing 100144 China.
RSC Adv. 2019 Jul 8;9(37):21202-21205. doi: 10.1039/c9ra02768h. eCollection 2019 Jul 5.
Easily prepared dual-responsive optical nanocomposite hydrogel (ONH) sensors which are responsive to tension and temperature are reported in which polymethyl methacrylate (PMMA) colloidal arrays were embedded into the hydrogels to obtain an optical response. Because of the band gap in the photonic crystal (PhC), the bright color of ONHs can be tuned by an external stimulus according to Bragg's law. Thermosensitive -isopropyl acrylamide (NiPAm) is added to the gel system, and by controlling NiPAm content and temperature, the contraction of the dual-response ONHs and the structural color response in the visible light range can change accordingly. Meanwhile, the temperature responses can be repeated more than seven times. Owing to the high biocompatibility, the excellent temperature response and the good mechanical strength of the ONHs, such optical biosensors have wide application in the biological field as an external stimulus sensor for implantable sensors, intracorporeal pressure measurement, and body temperature detection.
报道了一种易于制备的双响应光学纳米复合水凝胶（ONH）传感器，其对张力和温度有响应，其中聚甲基丙烯酸甲酯（PMMA）胶体阵列嵌入水凝胶中以获得光学响应。由于光子晶体（PhC）中的带隙，ONH的明亮颜色可根据布拉格定律通过外部刺激进行调节。将热敏性异丙基丙烯酰胺（NiPAm）添加到凝胶体系中，通过控制NiPAm含量和温度，双响应ONH的收缩以及可见光范围内的结构颜色响应会相应改变。同时，温度响应可重复七次以上。由于ONH具有高生物相容性、优异的温度响应和良好的机械强度，这种光学生物传感器作为用于可植入传感器、体内压力测量和体温检测的外部刺激传感器在生物领域具有广泛应用。
