Graduate School of Integrated Design Engineering, Keio University, 3-14-1 Hiyoshi, Kohoku-Ku, Yokohama, 223-8522, Japan.
Department of Mechanical Engineering, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-Ku, Yokohama, 223-8522, Japan.
Sci Rep. 2019 Nov 19;9(1):17059. doi: 10.1038/s41598-019-53499-2.
This paper presents eye-recognizable and repeatable biochemical flexible sensors using low angle-dependent stimuli-responsive photonic colloidal crystal hydrogel (PCCG) microbeads. Thanks to the stimuli-responsive PCCG microbeads exhibiting structural color, users can obtain sensing information without depending on the viewing angle and the mechanical deformation of the flexible sensor. Temperature-responsive PCCG microbeads and ethanol-responsive PCCG microbeads were fabricated from a pre-gel solution of N-isopropylacrylamide (NIPAM) and N-methylolacrylamide (NMAM) by using a centrifuge-based droplet shooting device (CDSD). As a proof-of-concept of thin and flexible biochemical sensors, temperature- and ethanol-sensing devices were demonstrated. By comparing the structural color of the stimuli-responsive PCCG microbeads and the color chart of the device, sensing information, including skin temperature of the human body and ethanol concentration in alcoholic beverages, was obtained successively. We expect that our device design using low angle-dependent stimuli-responsive PCCG microbeads would contribute to the development of user-friendly biochemical sensor devices for monitoring environmental and healthcare targets.
本文提出了一种使用低角度依赖刺激响应光子胶体晶体水凝胶（PCCG）微球的可识别眼睛和可重复的生化柔性传感器。由于刺激响应 PCCG 微球表现出结构色，用户可以在不依赖于观察角度和柔性传感器的机械变形的情况下获得传感信息。通过使用基于离心的液滴喷射装置（CDSD），从 N-异丙基丙烯酰胺（NIPAM）和 N-羟甲基丙烯酰胺（NMAM）的预凝胶溶液制备了温度响应 PCCG 微球和乙醇响应 PCCG 微球。作为薄型和柔性生化传感器的概念验证，演示了温度和乙醇感测装置。通过比较刺激响应 PCCG 微球的结构色和设备的色标，成功地获得了包括人体皮肤温度和酒精饮料中乙醇浓度在内的传感信息。我们期望我们使用低角度依赖刺激响应 PCCG 微球的设备设计将有助于开发用于监测环境和医疗保健目标的用户友好型生化传感器设备。
