Zheng Wenxiang, Cai Xiaolu, Yan Dan, Murtaza Ghulam, Meng Zihui, Qiu Lili
School of Chemistry and Chemical Engineering, Beijing Institute of Technology, Beijing 100081, China.
School of Materials Science and Engineering, Peking University, Beijing 100871, China.
Gels. 2022 May 30;8(6):339. doi: 10.3390/gels8060339.
Flexible wearable materials have frequently been used in drug delivery, healthcare monitoring, and wearable sensors for decades. As a novel type of artificially designed functional material, photonic crystals (PCs) are sensitive to the changes in the external environment and stimuli signals. However, the rigidity of the PCs limits their application in the field of biometric and optical sensors. This study selects silk fibroin (SF) and poly-N-isopropylacrylamide (PNIPAM) as principal components to prepare the hydrogel with the physical crosslinking agent lithium silicate (LMSH) and is then integrated with PCs to obtain the SF-PNIPAM dual-crosslinked nanocomposite for temperature and strain sensing. The structural colors of the PCs change from blue to orange-red by the variation in temperature or strain. The visual temperature-sensing and adhesion properties enable the SF-PNIPAM dual-crosslinked nanocomposite to be directly attached to the skin in order to monitor the real-time dynamic of human temperature. Based on its excellent optical properties and biocompatibility, the SF-PNIPAM dual-crosslinked nanocomposite can be applied to the field of visual biosensing, wearable display devices, and wound dressing materials.
几十年来，柔性可穿戴材料经常被用于药物递送、医疗监测和可穿戴传感器领域。作为一种新型的人工设计功能材料，光子晶体（PCs）对外部环境和刺激信号的变化敏感。然而，光子晶体的刚性限制了它们在生物识别和光学传感器领域的应用。本研究选择丝素蛋白（SF）和聚N-异丙基丙烯酰胺（PNIPAM）作为主要成分，与物理交联剂硅酸锂（LMSH）一起制备水凝胶，然后与光子晶体整合，以获得用于温度和应变传感的SF-PNIPAM双交联纳米复合材料。光子晶体的结构颜色会随着温度或应变的变化从蓝色变为橙红色。视觉温度传感和粘附特性使SF-PNIPAM双交联纳米复合材料能够直接附着在皮肤上，以监测人体温度的实时动态。基于其优异的光学性能和生物相容性，SF-PNIPAM双交联纳米复合材料可应用于视觉生物传感、可穿戴显示设备和伤口敷料材料领域。
