Jaglal S B, McAlister N H
CMAJ. 1987 Jun 1;136(11):1153-6.
Isolated systolic hypertension, characterized by elevated systolic blood pressure (greater than 150 to 165 mm Hg), normal diastolic blood pressure (less than 90 to 95 mm Hg) and, often, atherosclerosis, is now recognized as an important risk factor for cardiovascular disease. When the systolic pressure is 200 mm Hg or greater, or when it is 180 mm Hg or greater and accompanied by target organ damage, therapeutic intervention may be of value in patients under the age of 80 years. Low doses of thiazide diuretics have been shown to be safe and effective in lowering the systolic pressure. If the blood pressure remains high, treatment with methyldopa may be added.
单纯收缩期高血压的特征是收缩压升高（大于150至165毫米汞柱）、舒张压正常（小于90至95毫米汞柱），且常伴有动脉粥样硬化，目前被认为是心血管疾病的重要危险因素。当收缩压为200毫米汞柱或更高时，或当收缩压为180毫米汞柱或更高且伴有靶器官损害时，对于80岁以下的患者，治疗性干预可能具有价值。低剂量噻嗪类利尿剂已被证明在降低收缩压方面安全有效。如果血压仍然很高，可加用甲基多巴进行治疗。
