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精神科患者的自杀死亡风险与连续照护水平和地区贫困程度相关:一项基于人群的嵌套病例对照研究。

Risk of suicide death in psychiatric patients according to the level of continuity of care and area deprivation: A population-based nested case-control study.

机构信息

Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea; Institute of Health Services Research, Yonsei University, Seoul, 03722, Republic of Korea.

Department of Psychiatry, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Republic of Korea.

出版信息

J Psychiatr Res. 2022 Jul;151:279-285. doi: 10.1016/j.jpsychires.2022.04.024. Epub 2022 Apr 28.

DOI:10.1016/j.jpsychires.2022.04.024
PMID:35523068
Abstract

Continuity of care and area deprivation have been implicated as possible risk factors of suicide in psychiatric patients. This nested case-control study aimed to examine the association between continuity of care and area deprivation and suicide death in patients with psychiatric disorders. Data were collected from the Korean National Health Insurance Service National Sample Cohort, 2003-2013. The subjects were 974 patients with psychiatric disorders who completed suicides. Each case was compared to three control cases with propensity score matching by gender, age, and follow-up period with incidence density sampling, comprising the final control group of 2,922 living patients. Hazard ratios (HR) for suicide risk considering continuity of care and area deprivation were analysed using a multiple conditional logistic regression. The average follow-up periods between the case and control groups were not statistically different (case: 277.6 weeks, control: 271.4 weeks, p = .245). Both poor continuity of care and higher area deprivation proved to be associated with increased risk of suicide (poor continuity of care; adjusted HR [AHR]: 3.38, 95% confidence intervals [CI]: 2.58-4.43, highest area deprivation; AHR: 1.93, 95% CI: 1.53-2.44). Poor continuity of care combined with highest area deprivation showed a negative synergistic effect on a highly increased risk of suicide (AHR: 2.88, 95% CI: 1.45-5.74). Age was effect modified between suicide risk and poor continuity of care as well as suicide risk and higher area deprivation. A strong patient-provider relationship with good continuity of care may lead to a lower possibility of suicide in psychiatric patients. Moreover, improving community capacity for suicide prevention as well as appropriate postvention should be addressed.

摘要

连续性护理和地区贫困与精神科患者的自杀风险有关。本巢式病例对照研究旨在探讨连续性护理和地区贫困与精神障碍患者自杀死亡之间的关联。数据来自 2003-2013 年韩国国家健康保险服务国家样本队列。研究对象为 974 名完成自杀的精神障碍患者。采用倾向评分匹配按性别、年龄和随访期进行病例对照(发生率密度抽样),每个病例与 3 名对照匹配,最终对照组为 2922 名存活患者。采用多条件逻辑回归分析考虑连续性护理和地区贫困对自杀风险的危害比(HR)。病例组和对照组的平均随访期无统计学差异(病例组:277.6 周,对照组:271.4 周,p=0.245)。较差的连续性护理和较高的地区贫困都与自杀风险增加相关(较差的连续性护理;调整后的 HR [AHR]:3.38,95%置信区间 [CI]:2.58-4.43,最高地区贫困;AHR:1.93,95% CI:1.53-2.44)。较差的连续性护理与最高地区贫困相结合,对自杀风险有极强的协同作用(AHR:2.88,95% CI:1.45-5.74)。年龄对自杀风险与较差连续性护理以及自杀风险与较高地区贫困之间的关系具有修饰作用。与良好连续性护理建立牢固的医患关系可能会降低精神科患者自杀的可能性。此外,还应加强社区预防自杀的能力并采取适当的事后干预措施。

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